Evidence map›Paper›PMID 39786621›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Effects of oral intake, symptom severity, and sex difference on cancer patient prognosis.

Tetsuya Ito, Emi Tomizawa, Yuki Yano, Dai Akiyama, Haruko Konishi, Kiyozumi Takei, Masahiro Ikeda, Naoko Takahashi, Fumio Shaku

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tetsuya ItoDepartment of Palliative Medicine and Advanced Clinical Oncology, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. rachmaninov0531@gmail.com.
Emi TomizawaDepartment of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan.
Yuki YanoDepartment of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan.
Dai AkiyamaDepartment of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan.
Haruko KonishiDepartment of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan.
Kiyozumi TakeiDepartment of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan.
Masahiro IkedaDepartment of Palliative Medicine and Advanced Clinical Oncology, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Naoko TakahashiDepartment of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan.
Fumio ShakuDepartment of Psychosomatic Internal Medicine, Nihon University Itabashi Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFor cancer patients, prognostication by physicians constitutes a fundamental basis of decision-making to manage the cancer journey, especially with advanced stages of cancer. Various tools such as the palliative prognostic index (PPI) have been established to estimate patient survival. Such reliable and widely applied tools unfortunately provide unexpected results of prognosis predictions in some cases. To support disease-related decision-making, this study explores factors associated with prognosis prediction outliers in patients with advanced cancer in palliative care units (PCUs).

methodsFor this retrospective observational study conducted at a PCU, we surveyed medical records of patients with advanced cancer admitted to our facility during August 2018-June 2022. Specifically, we collected data for the PPI, laboratory data, physical status, and psychological symptoms on admission.

resultsOur survey of data of 675 patients revealed that the presence and absence of severely reduced oral intake were significantly associated, respectively, with shorter (p < 0.001) and longer (p < 0.001) than estimated survival. Moreover, symptoms other than pain and female sex were associated, respectively, with shorter-than-expected and longer-than-expected survival.

conclusionThe oral intake status of patients with advanced cancer in a PCU plays an important role in prognosis estimation. During prognosis, effects of symptoms other than pain and sex difference must also be considered. Although PPI-based prediction can provide a foundation for care management, cancer patients in more advanced stages of disease particularly require more detailed consideration.

Indexed as

NeoplasmsPalliative CareAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesSeverity of Illness IndexSex FactorsCancerOral intakePalliative care unitPPI: Palliative Prognostic IndexPrognosisSex difference

Identifiers

PMID39786621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.