Evidence map›Paper›PMID 39786486›Full record

Observational studyJournal of patient-reported outcomes2025

Patient-reported outcome measures to assess mental and physical health status, functionality, and quality of life in patients with major depression or schizophrenia.

Luis San, Belen Arranz, Carlota Romans, Berta García, Marta Coromina, Sonia Ortiz, Miriam Vilaplana, Víctor Soto, Ruth Villaescusa, Joan Alvaros

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Journal of patient-reported outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luis SanParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Belen ArranzParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain. Belen.arranz@sjd.es.ORCID 0000-0003-3927-8803
Carlota RomansParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Berta GarcíaParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Marta CorominaParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Sonia OrtizParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Miriam VilaplanaParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Víctor SotoParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Ruth VillaescusaParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.
Joan AlvarosParc Sanitari Sant Joan de Déu, General Hospital, C/ Doctor Antoni Pujadas 42, Sant Boi de Llobregat, Barcelona, E-08830, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient-reported outcomes measures (PROMs) are standardized self-administered tools that assess the patient's opinion on the level of health, quality of life, and disability among other aspects. The objective of this study was to gather information on physical and mental health in patients with major mental illness using PROMs.

methodsThis was an observational, naturalistic, prospective study carried out in adult stabilized outpatients attended at nine Adult Mental Health Centers in Barcelona, Spain. All participants had a confirmed diagnosis of major depression disorder or schizophrenia (DSM-5) and were currently on drug treatment. Participants (n = 508) self-completed a baseline questionnaire for clinical data and PROMs scales (PHQ-19, SF-12, and WHODAS 2.0) at baseline and 9 months thereafter (n = 482).

resultsMean (SD) age was 50.9 (13.2) years, and 83% of patients lived with their families. Although 93.9% of patients recognized having a mental illness, 15.7% did not know their diagnosis. When asked if they considered that during the last year their treatment had offered some type of improvement, 83.9% answered affirmatively. Patients reported that their degree of adherence to treatment was high (77%) and most of them (80%) believed the medication had a beneficial effect. Depressed patients showed both at baseline and at follow up significantly more depressive symptoms than the group with schizophrenia. In the schizophrenia group, a statistically significant improvement in depressive symptoms was noted at 9 months follow-up. We did not find significant differences within or between groups in quality of life (SF-12 scores) obtained at baseline and after 9 months of follow-up Both at baseline and at follow-up, patients with depression reported a significantly higher degree of disability (WHODAS scores) than those with schizophrenia.

conclusionsPROMs can be used in real-world conditions to assess severity of disease, quality of life, and disability in major depression and schizophrenia. The present results are relevant for both patients and clinicians.

Indexed as

Health StatusMajor Depressive DisorderPatient Reported Outcome MeasuresQuality of LifeSchizophreniaAdultAgedFemaleHumansMaleMental HealthMiddle AgedProspective StudiesSpainSurveys and QuestionnairesAdult patientsMajor depressionPatient-reported outcome measures (PROMS)Schizophrenia

Identifiers

PMID39786486
PMCPMC11718024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.