Evidence map›Paper›PMID 39786483›Full record

Trial reportClinical oral investigations2025

The plaque reducing efficacy of oil pulling with sesame oil: a randomized-controlled clinical study.

Christine Zürcher, Kristian Vukoje, Eva Maria Kleiner, Sophie Martina Kuster, Lisa Katharina Jäger-Larcher, Ingrid Heller, Sigrun Eick, Markus Nagl, Ines Kapferer-Seebacher

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06327841 (The Plaque Reducing Efficacy of Oil Pulling With Sesame Oil. A Randomized-controlled Clinical Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06327841 nacompletednot on this map

The Plaque Reducing Efficacy of Oil Pulling With Sesame Oil. A Randomized-controlled Clinical Study

TypeinterventionalSponsorMedical University InnsbruckRan2022 to 2022Enrolled40ConditionsDental Plaque, Gingivitis, Oral Microbial ColonizationArmssesame oil, distilled water
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christine ZürcherUniversity Hospital for Conservative Dentistry and Periodontology, Medical University of Innsbruck, Innsbruck, 6020, Austria.
Kristian VukojeUniversity Hospital for Dental Prosthetics, Medical University of Innsbruck, Innsbruck, Austria.
Eva Maria KleinerUniversity Hospital for Conservative Dentistry and Periodontology, Medical University of Innsbruck, Innsbruck, 6020, Austria.
Sophie Martina KusterUniversity Hospital for Conservative Dentistry and Periodontology, Medical University of Innsbruck, Innsbruck, 6020, Austria.
Lisa Katharina Jäger-LarcherUniversity Hospital for Conservative Dentistry and Periodontology, Medical University of Innsbruck, Innsbruck, 6020, Austria.
Ingrid HellerInstitute of Hygiene & Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Sigrun EickDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Markus Nagl *Institute of Hygiene and Medial Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Ines Kapferer-Seebacher *University Hospital for Conservative Dentistry and Periodontology, Medical University of Innsbruck, Innsbruck, 6020, Austria. ines.kapferer@i-med.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the plaque reducing efficacy of oil pulling with sesame oil compared to distilled water in a randomized, controlled, examiner-blinded parallel group study. MATERIALS AND

methodsForty probands without advanced periodontal disease of the University Hospital for Restorative Dentistry and Periodontology, Medical University of Innsbruck (Austria) were randomized allocated to test- (sesame oil) or control group (distilled water) and asked to pull daily in the morning for eight weeks with their allotted fluid for 15 min. Rustogi Modified Navy Plaque Index (RMNPI) and gingival bleeding index were assessed at baseline and after four and eight weeks. Plaque samples underwent microbiological analysis.

resultsPulling with sesame oil was significantly more effective in reducing full mouth RMNPI compared to distilled water after eight weeks (median reduction 18.98% versus 10.49%; p = 0.023), and was most pronounced in anterior, buccal, and lingual subscales. On approximal surfaces, significantly higher plaque reduction was found in the test group after four (24.07% versus 14.29%) and eight weeks (16.00% versus 5.36%) of intervention (p < 0.05). No significant changes in gingival index and mirobiological analysis could be detected.

conclusionPlaque reduction was statistically significantly higher with oil pulling than with distilled water, however, a study bias cannot be ruled out. Further high-quality trials are needed to understand the mechanisms and effectiveness of oil pulling, to finally clarify the evidence. CLINICAL RELEVANCE: Oil pulling may be recommended as an adjuvant to mechanical dental cleaning. Individuals with keratosis may experience adverse effects.

trial registrationClinicalTrials.gov NCT06327841.

Indexed as

Dental PlaqueDental Plaque IndexPeriodontal IndexSesame OilAdultFemaleHumansMaleMiddle AgedSingle-Blind MethodTreatment OutcomeWaterSesame OilWaterDental biofilm(s)Oil pullingOral hygienePlaque indexSesame oil

Identifiers

PMID39786483
PMCPMC11717832

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.