Evidence map›Paper›PMID 39786433›Full record

Observational studyRheumatology international2025

Increase in comorbidities with age among patients with psoriatic arthritis: a multicenter observational study.

S Chandrashekara, Padmanabha Shenoy, Uma Kumar, Sapan Pandya, Alakendu Ghosh, Apurva Khare, Rajkiran Dudam, Rudra Prosad Goswami

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S ChandrashekaraChanRe Rheumatology and Immunology Center and Research, Bengaluru, India. chandrashekara_s@yahoo.com.ORCID 0000-0003-2661-9840
Padmanabha ShenoyCentre for Arthritis & Rheumatism Excellence (CARE), Cochin, Kerala, India.ORCID 0000-0002-7666-1361
Uma KumarDepartment of Rheumatology, All India Institute of Medical Science, New Delhi, India.ORCID 0000-0003-3281-7683
Sapan PandyaRheumatic Disease Clinic, 4th floor, Vedanta Institute of Medical Science, Commerce College Road, 380009, Navrangpura, Ahmedabad, Gujarat, India.ORCID 0000-0002-1701-368X
Alakendu GhoshClinical Immunology & Rheumatology Institute of Post-Graduate, Medical Education and Research, 700020, Kolkata, India.ORCID 0000-0003-2956-9703
Apurva KhareDepartment of General Medicine, LN Medical College and Research Center, Kolar Road, 462042, Bhopal, Madhya Pradesh, India.ORCID 0000-0001-8693-7512
Rajkiran DudamHRC Hospital, Prakash Nagar Begumpet, Hyderabad, India.ORCID 0000-0003-1387-5183
Rudra Prosad GoswamiDepartment of Rheumatology, AIIMS, New Delhi, India.ORCID 0000-0001-8670-1745

Funding

Novartis Novartis
6 · The paper itself

Abstract

backgroundPsoriatic arthritis (PsA) significantly contributes to increased morbidity, reduced life expectancy, and higher healthcare costs due to the burden of comorbidities. This study assessed the prevalence of comorbidities in PsA patients in India and explored the influence of age and disease duration on these comorbidities.

methodsThe prospective, multicenter observational study was conducted across seven centers in India, utilizing data from the Indian Rheumatology Association. Data were collected using expert-validated proformas, with comorbidities classified according to the ICD-10 Charlson Comorbidity Index. Participants were divided into two age groups: <40 years and ≥ 40 years.

resultsThe study included 533 participants (median age: 50 years, range: 17-81). Comorbidities were more common among older patients (median age: 54 years, range: 41-79). About 38% had at least one comorbidity, with hypertension (17.07%) and diabetes (15.19%) being most prevalent, followed by thyroid disorders (10.13%) and hyperlipidemia (3.94%). Comorbidities were significantly more common in patients ≥ 40 years (45.04%) compared to those < 40 years (18.57%) (P < 0.001). The older group also had higher rates of hyperlipidemia (4.83% vs. 0.71%, P = 0.035) and hypertension (22.14%). Logistic regression revealed a significant association between age and the prevalence of diabetes, hypertension, and thyroid disorders (P = 0.003). Among patients over 40, 44.27% had at least one comorbidity.

conclusionThe study underscores the significant association between age and the prevalence of comorbidities in PsA patients, particularly in those over 40 years. These findings highlight the importance of targeted screening and management in older PsA patients.

Indexed as

Arthritis, PsoriaticComorbidityAdolescentAdultAgedAged, 80 and overAge FactorsDiabetes MellitusFemaleHumansHyperlipidemiasHypertensionIndiaMaleMiddle AgedPrevalenceArthritisComorbidityDiabetes MellitusHyperlipidemiasHypertensionPsoriatic

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.