Evidence map›Paper›PMID 39785720›Full record

ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)2025

Childhood family adversity and recurrent depression in adulthood: the findings of three ELSA-Brasil follow-up visits.

Maíra Barroso Léo, Sandhi Maria Barreto, Rosane Harter Griep, Ana Luísa Patrão, Lidyane do Valle Camelo, Maria Carmen Viana, Luana Giatti

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In one paragraph

Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Maíra Barroso LéoPrograma de Pós-Graduação em Saúde Pública, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
Sandhi Maria BarretoPrograma de Pós-Graduação em Saúde Pública, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. Hospital das Clínicas/Empresa Brasileira de Serviços Hospitalares, Faculdade de Medicina, UFMG, Belo Horizonte, MG, Brazil.
Rosane Harter GriepLaboratório de Educação em Ambiente e Saúde, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Ana Luísa PatrãoCentro de Psicologia da Universidade do Porto, Faculdade de Psicologia e Ciências da Educação, Universidade do Porto, Porto, Portugal. Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, BA, Brazil.
Lidyane do Valle CameloPrograma de Pós-Graduação em Saúde Pública, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. Faculdade de Medicina, UFMG, Belo Horizonte, MG, Brazil.
Maria Carmen VianaDepartamento de Medicina Social, Universidade Federal do Espírito Santo, Vitória, ES, Brazil.
Luana GiattiPrograma de Pós-Graduação em Saúde Pública, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. Hospital das Clínicas/Empresa Brasileira de Serviços Hospitalares, Faculdade de Medicina, UFMG, Belo Horizonte, MG, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Departamento de Ciência e TecnologiaFinanciadora de Estudos e Projetos
6 · The paper itself

Abstract

objectiveThis study investigated the association between childhood family adversity and depression in a cohort of Brazilian adults over three visits.

methodsA total of 12,636 participants from the Longitudinal Study of Adult Health (ELSA-Brasil), baseline (2008-2010) and followed up in 2012-2014 and 2017-2019, were included. Five types of family dysfunction and the childhood family dysfunction score (0, 1, and = 2 dysfunctions) were used. The Clinical Interview Schedule-Revised was used to assess depression in visits 1 and 2 or 3. Multinomial logistic regression models estimated crude and adjusted OR and 95%CI.

resultsThe mean age of the sample was 59.6 (SD, 8.8) years, 7.4% presented depression in one visit, and 2.2% presented it in two or three visits. After adjustment, compared to no family dysfunction, mental disorder (OR = 3.91; 95%%CI 2.94-5.21), substance abuse (OR = 2.14; 95%CI 1.65-2.77), and parental separation/divorce (OR = 1.55; 95%CI 1.12-2.15) increased the odds of depression in two or three visits. Exposure to = 2 types of family dysfunction increased the odds of depression in one, and two or three visits in a dose-response gradient.

conclusionExposure to childhood family dysfunction contributes to the occurrence and recurrence of depression in adults. Interventions to prevent dysfunctional family environments and their repercussions on children can reduce the burden of depression.

Indexed as

Adverse Childhood ExperiencesDepressionAdultAgedBrazilChildFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedRecurrenceRisk FactorsSocioeconomic FactorsAdverse childhood experienceschildhood traumacohort studydepression

Identifiers

PMID39785720
PMCPMC12812381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.