Evidence map›Paper›PMID 39785229›Full record

ArticlePediatric pulmonology2025

Pulmonary Function Testing in Healthy Infants in Rural Bangladesh: Feasibility Study.

Charl Verwey, Hm Golam Kibria Sojib, Md Shafiqul Islam, Arunangshu Dutta Roy, Md Asmd Ashraful Islam, Nabidul H Chowdhury, Dorottya Czovek, Gergely Makan, Salahuddin Ahmed, Abdullah H Baqui and 2 more

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In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Charl VerweyFaculty of Health Sciences, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-1756-7068
Hm Golam Kibria SojibProjahmo Research Foundation, Dhaka, Bangladesh.
Md Shafiqul IslamProjahmo Research Foundation, Dhaka, Bangladesh.
Arunangshu Dutta RoyProjahmo Research Foundation, Dhaka, Bangladesh.
Md Asmd Ashraful IslamProjahmo Research Foundation, Dhaka, Bangladesh.
Nabidul H ChowdhuryProjahmo Research Foundation, Dhaka, Bangladesh.ORCID http://orcid.org/0000-0002-6149-1152
Dorottya CzovekDepartment of Paediatrics, Semmelweis University, Budapest, Hungary.
Gergely MakanDepartment of Technical Informatics, University of Szeged, Szeged, Hungary.
Salahuddin AhmedProjahmo Research Foundation, Dhaka, Bangladesh.
Abdullah H BaquiDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Zoltan HantosDepartment of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Eric D McCollumDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

Funding

This work was funded by the United States National Institute of Environmental Health Sciences (R21ES029330 to E.D.M.) and Hungarian Scientific Research Fund (K105403, FK 129237 and K128701 to D.C. and Z.H.).
6 · The paper itself

Abstract

backgroundInfant pulmonary function testing (iPFT) in low- and middle-income countries is limited. We evaluated the early feasibility of iPFT in rural Bangladesh.

methodsExperts established an iPFT laboratory at Zakiganj Upazila Health Complex in Sylhet, Bangladesh and trained staff. Infants ≤ 6 months old participating in a cohort study between 2021 and 2022 were eligible for respiratory oscillometry (Osc), tidal breath flow-volume loops (TBFVL), and sulphur hexaflouride multiple breath washout (MBW) during natural sleep. Participants with a respiratory infection within 4 weeks were not tested. Among the first 25 infants with attempted Osc, TBFVL, or MBW measurements, we report the test proportions meeting international quality standards, measurement averages, and the mean measurement differences between laboratory staff and experts.

resultsAmong the first 25 eligible infants with attempted measurements, acceptable Osc measurements were achieved in 88% (22/25), TBFVL in 96% (24/25), and MBW in 88% (22/25). Infants tested by Osc at 2 months were a median (IQR) of 81 days old (73, 85) and tested at 6 months were a median of 194 days old (193, 202); TBFVL/MBW tested infants were a mean 83 days (79, 87). Mean (SD) Osc resistance at 7 Hz was 66.3 (25.2) and 64.0 (22.4) hPa.s.L

conclusionsEstablishing an iPFT laboratory and performing quality measurements and expert-level interpretations in rural Bangladesh is feasible.

Indexed as

Feasibility StudiesRespiratory Function TestsRural PopulationBangladeshCohort StudiesFemaleHumansInfantInfant, NewbornMale

Identifiers

PMID39785229
PMCPMC11715148

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.