Evidence map›Paper›PMID 39785198›Full record

ArticlePediatric pulmonology2025

Upper Extremity Exercise Capacity and Muscle Oxygenation in Patients With Primary Ciliary Dyskinesia.

Şeyma Mutlu, Meral Boşnak Güçlü, Tuğba Şişmanlar Eyüboğlu, Ayşe Tana Aslan

2 registry-linked trialsAbstract read
In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07148362 completednot on this map

Comparison of Upper Extremity Exercise Capacity, Muscle Oxygenation, and Balance in Pediatric Cystic Fibrosis and Primary Ciliary Dyskinesia

TypeobservationalSponsorGazi UniversityRan2021 to 2025Enrolled88ConditionsCystic Fibrosis (CF), Primary Ciliary Dyskinesia (PCD)
NCT07157644 completednot on this map

Comparison of Functional Exercise Capacity, Muscle Oxygenation, Respiratory Muscle Strength, and Physical Activity Level in Pediatric Cystic Fibrosis and Primary Ciliary Dyskinesia

TypeobservationalSponsorGazi UniversityRan2021 to 2025Enrolled88ConditionsCystic Fibrosis (CF), Primary Ciliary Dyskinesia (PCD)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Nutrition and growth of primary ciliary dyskinesia patients: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Şeyma MutluDepartment of Physical Therapy and Rehabilitation, Faculty of Health Sciences, Başkent University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-1745-2631
Meral Boşnak GüçlüDepartment of Physical Therapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-3861-9912
Tuğba Şişmanlar EyüboğluDepartment of Pediatric Chest Diseases, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-7284-4999
Ayşe Tana AslanDepartment of Pediatric Chest Diseases, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-5360-8517

Funding

Gazi University Projects of Scientific Investigation.
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPatients with primary ciliary dyskinesia (PCD) have a reduction in exercise capacity from the early stages. Although there are studies investigating these patients' lower extremity exercise capacity using various methodologies, there needs to be more research on the functional exercise capacity of the upper extremities. This study aimed to compare pulmonary function, upper extremity functional exercise capacity, muscle oxygenation, muscle strength, and physical activity level in children with PCD and controls.

methodsTwenty-seven children with PCD and 26 controls were included. Pulmonary function (spirometry), upper extremity functional exercise capacity (6-min pegboard and ring test (6PBRT), muscle oxygenation (Moxy device), deltoid muscle strength (dynamometer), and physical activity level (metabolic holter) were assessed.

resultsPatients' FVC%, FEV DISCUSSION: Pulmonary function deteriorates and upper extremity muscle strength decreases in children with PCD. The upper extremity exercise capacity of these patients remains preserved. However, upper extremity resting muscle oxygen saturation is lower in children compared to healthy children. Most patients and healthy children are inactive. The upper extremity exercise capacity possibly declines due to deteriorating pulmonary function as the patients get older, which needs to be investigated routinely. Both upper-lower extremity aerobic exercise training applied consistently and physical activity counseling as part of their pulmonary rehabilitation program should be considered in children with PCD.

Indexed as

Exercise ToleranceMuscle StrengthUpper ExtremityAdolescentCase-Control StudiesChildExercise TestFemaleHumansMaleRespiratory Function Testsexercise toleranceoxygen saturationphysical activityprimary ciliary dyskinesiaupper extremity

Identifiers

PMID39785198
PMCPMC11715149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.