Evidence map›Paper›PMID 39785103›Full record

SynthesisInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2025

Impacts of Ramadan fasting during pregnancy on pregnancy and birth outcomes: An umbrella review.

Abdullah Al-Taiar, Md Estiar Rahman, May Salama, Ali H Ziyab, Wilfried Karmaus

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impacts of Ramadan fasting during pregnancy on pregnancy and birth outcomes: An umbrella review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdullah Al-TaiarJoint School of Public Health, Macon and Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, Virginia, USA.ORCID https://orcid.org/0000-0001-7421-3381
Md Estiar RahmanJoint School of Public Health, Macon and Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, Virginia, USA.ORCID https://orcid.org/0000-0003-1372-2603
May SalamaJoint School of Public Health, Macon and Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, Virginia, USA.ORCID https://orcid.org/0000-0002-1637-407X
Ali H ZiyabDepartment of Community Medicine and Behavioral Sciences, College of Medicine, Kuwait University, Safat, Kuwait.ORCID https://orcid.org/0000-0003-3099-4424
Wilfried KarmausDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, Tennessee, USA.ORCID https://orcid.org/0000-0003-2684-1492

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite a large number of primary research studies, and systematic and narrative reviews, there is no consensus on the impact of fasting during Ramadan while pregnant on pregnancy and birth outcomes. Currently, there is no evidence-based guideline for Muslim women regarding Ramadan fasting during pregnancy and clinicians cannot provide firm recommendations.

objectivesTo review the current evidence regarding the impact of Ramadan fasting during pregnancy on pregnancy and birth outcomes. SEARCH STRATEGY: We conducted an umbrella review of all systematic and narrative reviews examining the impacts of fasting during Ramadan while pregnant on pregnancy and birth outcomes by searching PubMed, CINAHL, and Cochrane Registry of Systematic Reviews databases between November 2023 and February 2024. SELECTION CRITERIA: We included all systematic and narrative reviews examining the impacts of Ramadan fasting on pregnancy and birth outcomes. The primary outcome was the change in birth weight, gestational age at birth, fetal growth indices, and Apgar score as well as the risk of delivery by cesarean section and the risks of gestational diabetes and pre-eclampsia. DATA COLLECTION AND ANALYSIS: We summarized the data using narrative synthesis and descriptive statistics as appropriate. This study was registered with PROSPERO, ID: CRD42023478819. MAIN

resultsOut of 943 published reports identified across all database searches, 13 systematic and narrative reviews were included, of which three were systematic reviews with meta-analysis, six were systematic reviews without meta-analysis, and the remaining four were narrative reviews. There is no sufficient evidence that Ramadan fasting during pregnancy may reduce gestational age at birth or increase the risk of preterm birth (PTB). There is little evidence to support the hypothesis that maternal Ramadan fasting may reduce birth weight or increase the risk of low birth weight (LBW). Systematic reviews showed pooled estimates of odds ratios ranging between 0.93 (95% confidence interval [CI] 0.60-1.44) and 0.99 (95% CI 0.72-1.37) for PTB, and between 1.05 (95% CI 0.87-1.26) and 1.37 (95% CI 0.74-2.53) for LBW. There is no sufficient evidence that Ramadan fasting during pregnancy may increase the risk of delivery by cesarean section, gestational diabetes, or the risk of pre-eclampsia. None of the reviews reported evidence regarding the impacts of fasting during pregnancy on rare but clinically significant pregnancy and birth outcomes such as stillbirth, miscarriage, congenital anomalies, or neonatal deaths.

conclusionThere is little evidence that Ramadan fasting during pregnancy can negatively impact pregnancy and birth outcomes. Primary research studies on this issue suffered from significant methodologic limitations and systematic reviews showed significant heterogeneity for several pregnancy and birth outcomes. High-quality primary research studies that collect data on multiple confounders and effect modifiers are needed to investigate this issue and help reaching evidence-based recommendations.

Indexed as

FastingIslamPregnancy OutcomeApgar ScoreBirth WeightCesarean SectionDiabetes, GestationalFemaleGestational AgeHumansInfant, NewbornPre-EclampsiaPregnancyPregnancy Complicationsbirth outcomebirth weightfastingpregnancypreterm birthRamadan

Identifiers

PMID39785103
PMCPMC12093917

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.