Evidence map›Paper›PMID 39783858›Full record

ArticleeLife2025

Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells.

Dominic Gonschorek, Matías A Goldin, Jonathan Oesterle, Tom Schwerd-Kleine, Ryan Arlinghaus, Zhijian Zhao, Timm Schubert, Olivier Marre, Thomas Euler

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Retinal Neurochemistry.Brain sciences · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominic GonschorekWerner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.ORCID https://orcid.org/0000-0001-5118-9817
Matías A GoldinInstitut de la Vision, Sorbonne Université, INSERM, CNRS, Paris, France.
Jonathan OesterleWerner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.ORCID https://orcid.org/0000-0001-8919-1445
Tom Schwerd-KleineWerner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.
Ryan ArlinghausWerner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.
Zhijian ZhaoInstitute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.ORCID https://orcid.org/0000-0002-3302-1495
Timm SchubertWerner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.
Olivier MarreInstitut de la Vision, Sorbonne Université, INSERM, CNRS, Paris, France.
Thomas EulerWerner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.ORCID https://orcid.org/0000-0002-4567-6966

Funding

Agence Nationale de la Recherche PerBaCoDeutsche Forschungsgemeinschaft 335549539Deutsche Forschungsgemeinschaft CRC 1233 - 276693517Deutsche Forschungsgemeinschaft GRK2381
6 · The paper itself

Abstract

Neuromodulators have major influences on the regulation of neural circuit activity across the nervous system. Nitric oxide (NO) has been shown to be a prominent neuromodulator in many circuits and has been extensively studied in the retina. Here, it has been associated with the regulation of light adaptation, gain control, and gap junctional coupling, but its effect on the retinal output, specifically on the different types of retinal ganglion cells (RGCs), is still poorly understood. In this study, we used two-photon Ca

Indexed as

Nitric OxideRetinal Ganglion CellsAnimalsCalciumMiceMice, Inbred C57BLPhotic StimulationCalciumNitric Oxideganglion cellsmouseneuromodulationneurosciencenitric oxideretina

Identifiers

PMID39783858
PMCPMC11717361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.