Evidence map›Paper›PMID 39781894›Full record

ArticleAnalytical chemistry2025

Comprehensive Approach for Sequential MALDI-MSI Analysis of Lipids,

Yea-Rin Lee, Ibrahim Kaya, Elin Wik, Sooraj Baijnath, Henrik Lodén, Anna Nilsson, Xiaoqun Zhang, Dag Sehlin, Stina Syvänen, Per Svenningsson and 1 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yea-Rin LeeDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden.
Ibrahim KayaDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden.
Elin WikDepartment of Public Health and Caring Sciences, Uppsala University, SE-75237 Uppsala ,Sweden.
Sooraj BaijnathDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden.
Henrik LodénDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden.ORCID 0000-0002-2416-5251
Anna NilssonDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden.
Xiaoqun ZhangDepartment of Clinical Neuroscience, Karolinska Institute, SE-17177 Stockholm ,Sweden.
Dag SehlinDepartment of Public Health and Caring Sciences, Uppsala University, SE-75237 Uppsala ,Sweden.ORCID 0000-0002-9430-3859
Stina SyvänenDepartment of Public Health and Caring Sciences, Uppsala University, SE-75237 Uppsala ,Sweden.ORCID 0000-0002-8196-4041
Per SvenningssonDepartment of Clinical Neuroscience, Karolinska Institute, SE-17177 Stockholm ,Sweden.
Per E AndrénDepartment of Pharmaceutical Biosciences, Spatial Mass Spectrometry, Science for Life Laboratory, Uppsala University, SE-75124 Uppsala ,Sweden.ORCID 0000-0002-4062-7743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiomics analysis of single tissue sections using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) provides comprehensive molecular insights. However, optimizing tissue sample preparation for MALDI-MSI to achieve high sensitivity and reproducibility for various biomolecules, such as lipids,

Indexed as

BrainBrain ChemistryLipidsPeptidesPolysaccharidesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAlzheimer DiseaseAnimalsDisease Models, AnimalMiceMice, TransgenicRatsLipidsPeptidesPolysaccharides

Identifiers

PMID39781894
PMCPMC11755403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.