Evidence map›Paper›PMID 39781576›Full record

ArticleCancer medicine2025

Patient and Caregiver Perceptions of Caregiving Contributions During Cancer Clinical Trials: A Mixed-Methods Study.

Janine Cerutti, Maria C Lent, Randall F Holcombe, Maija Reblin

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Considering the caregiver in early-phase clinical trials: a review of trial protocols and consent forms.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Janine CeruttiDepartment of Psychological Science, The University of Vermont, Burlington, Vermont, USA.ORCID https://orcid.org/0000-0002-9280-4406
Maria C LentDepartment of Psychological Science, The University of Vermont, Burlington, Vermont, USA.
Randall F HolcombeUniversity of Vermont Cancer Center, University of Vermont, Burlington, Vermont, USA.ORCID https://orcid.org/0000-0002-7417-0390
Maija ReblinUniversity of Vermont Cancer Center, University of Vermont, Burlington, Vermont, USA.ORCID https://orcid.org/0000-0003-3108-465X

Funding

University of Vermont Cancer Center
6 · The paper itself

Abstract

objectiveCaregivers play crucial roles in cancer treatment and outcomes. However, little is known regarding how caregivers support patients during cancer clinical trials. The aim of this study was to gain insight into the caregiver experience of rural and urban patients enrolled in cancer clinical trials.

methodsAs part of a quality improvement study, 21 patient-caregiver dyads were interviewed using closed and open-ended interview questions. We analyzed quantitative and qualitative data on patient and caregiver perceptions of caregiver contributions and explored differences in the reported caregiving experience between rural and urban participants.

resultsWhile patient-caregiver dyads showed significant disagreement in the symptoms/medication management domain, with caregivers tending to acknowledge the contribution while patients did not (χ

conclusionOur study revealed that caregivers are assisting patients in often unseen and underestimated ways during cancer clinical trials, highlighting their multifaceted role. Cancer clinical trials should implement a family-centered approach, especially for rural caregivers, to enhance patient retention and outcomes.

Indexed as

CaregiversClinical Trials as TopicNeoplasmsRural PopulationAdultAgedFemaleHumansMaleMiddle AgedPerceptionQualitative ResearchSocial SupportUrban Populationcancercaregiversclinical trialmixed methodsoncologyqualitative researchrural

Identifiers

PMID39781576
PMCPMC11712184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.