Evidence map›Paper›PMID 39781538›Full record

ArticleNature. Mental health2024

What should constitute a control condition in psychedelic drug trials?

Luana Colloca, Maurizio Fava

Abstract read
In one paragraph

Article in Nature. Mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Ketamine-induced analgesia and dissociation show distinct behavioral and neural correlates.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  3. Article
  4. Review
  5. Causal Inference in Studies with Functional Unmasking: Psychedelics and Beyond.medRxiv : the preprint server for health sciences · 2026
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Luana CollocaDepartment of Pain and Translational Symptom Science, Placebo Beyond Opinions Center, University of Maryland School of Nursing, Baltimore, MD, USA.ORCID 0000-0002-6503-4709
Maurizio FavaDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

Funding

Neural correlates of hypoalgesia driven by observationR01AT010333 · NCCIH · UNIVERSITY OF MARYLAND BALTIMORE · PI COLLOCA, LUANA · 2019 to 2023
$3.7M
Neural Mechanisms of Immersive Virtual Reality in Chronic PainR01AT011347 · NCCIH · UNIVERSITY OF MARYLAND BALTIMORE · PI Luana Colloca · 2021 to 2026
$3.2M
NCCIH NIH HHS R01 AT010333NCCIH NIH HHS R01 AT011347
6 · The paper itself

Abstract

Over the past decade there has been a surge in interest in placebo-controlled trials using non-classical 3,4-methylenedioxymethamphetamine (MDMA) and classical psychedelics such as psilocybin, lysergic acid diethylamide (LSD) and

Identifiers

PMID39781538
PMCPMC11709123

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.