Cholesterol concentration is associated with neither prognosis nor bacterial infection type in septic dogs.

Veronica Perez-Rodriguez, Alexis Kidd, James Colee, Jake Wolf

Abstract read

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Veronica Perez-RodriguezDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, PO Box 100126, Gainesville, Florida 32610-012, USA (Perez-Rodriguez, Kidd, Wolf); IFAS Statistical Consulting, University of Florida, 402 McCarty Hall C, PO Box 110339, Gainesville, Florida 32611-0339, USA (Colee).

Alexis KiddDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, PO Box 100126, Gainesville, Florida 32610-012, USA (Perez-Rodriguez, Kidd, Wolf); IFAS Statistical Consulting, University of Florida, 402 McCarty Hall C, PO Box 110339, Gainesville, Florida 32611-0339, USA (Colee).

James ColeeDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, PO Box 100126, Gainesville, Florida 32610-012, USA (Perez-Rodriguez, Kidd, Wolf); IFAS Statistical Consulting, University of Florida, 402 McCarty Hall C, PO Box 110339, Gainesville, Florida 32611-0339, USA (Colee).

Jake WolfDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, PO Box 100126, Gainesville, Florida 32610-012, USA (Perez-Rodriguez, Kidd, Wolf); IFAS Statistical Consulting, University of Florida, 402 McCarty Hall C, PO Box 110339, Gainesville, Florida 32611-0339, USA (Colee).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective was to assess whether cholesterol concentration at admission was associated with outcome and disease severity in dogs with sepsis, and to determine whether there was a significant difference in cholesterol between dogs with gram-positive Animals and procedure: Electronic medical records of dogs diagnosed with sepsis at a tertiary teaching hospital from 2012 to 2022 were evaluated. A total of 299 dogs were included. Data obtained included signalment, comorbidities, cholesterol concentration, culture results, duration of hospitalization, cost of hospitalization, and outcome. An acute patient physiological and laboratory evaluation fast score (APPLE Results: In septic dogs, there was no significant difference in cholesterol concentration between survivors and non-survivors. Cholesterol concentration was not significantly associated with disease severity in dogs with sepsis and there was no significant difference in cholesterol concentration between dogs with grampositive Conclusion and clinical relevance: There were no significant correlations between cholesterol concentration and outcome, disease severity, or bacterial type in dogs with sepsis. Therefore, cholesterol does not appear to be a reliable biomarker of sepsis in dogs. Further research is warranted to understand the role of lipids in response to sepsis in dogs.

Indexed as

CholesterolDog DiseasesSepsisAnimalsBiomarkersDogsFemaleGram-Negative Bacterial InfectionsGram-Positive Bacterial InfectionsMalePrognosisRetrospective StudiesBiomarkersCholesterol

Identifiers

PMID39781406

PMCPMC11705171

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.