Evidence map›Paper›PMID 39781347›Full record

ArticleJournal of Cancer2025

ADAMTS7 Enhances Gastric Cancer Growth and Metastasis by Triggering the NF-κB Signaling Pathway.

Shun Chen, Jiancheng He, Hanxu Gao, Xian Gao, Lingchen Dai, Junjie Chen, Zhenyu Sha

Abstract read
In one paragraph

Article in Journal of Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shun ChenDepartment of Gastrointestinal Surgery, Affiliated Hospital and Medical School of Nantong University, Nantong 226001, China.
Jiancheng HeDepartment of Gastrointestinal Surgery, Affiliated Hospital and Medical School of Nantong University, Nantong 226001, China.
Hanxu GaoDepartment of Gastrointestinal Surgery, Affiliated Hospital and Medical School of Nantong University, Nantong 226001, China.
Xian GaoDepartment of Gastrointestinal Surgery, Affiliated Hospital and Medical School of Nantong University, Nantong 226001, China.
Lingchen DaiDepartment of Gastrointestinal Surgery, Affiliated Hospital and Medical School of Nantong University, Nantong 226001, China.
Junjie ChenResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Zhenyu ShaHigh Quality Development Assessment Office, Affiliated Hospital of Nantong University, No 20, Xisi Road, Nantong 226001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family of metalloproteinases plays a vital role in various biological and pathological processes, including tissue remodeling, angiogenesis, and cancer progression. Among the 19 ADAMTS family members, our research focused on ADAMTS7, which exhibited significant overexpression in gastric cancer (GC). This overexpression was strongly correlated with poor clinical outcomes, including reduced overall survival and heightened metastatic potential. To investigate the role of ADAMTS7 in GC, we employed an integrated approach encompassing bioinformatics analysis, Western blotting, immunofluorescence, as well as

Indexed as

ADAMTS7Gastric cancerMetastasisNF-κBProliferation

Identifiers

PMID39781347
PMCPMC11705055

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.