Evidence map›Paper›PMID 39781205›Full record

ReviewMediastinum (Hong Kong, China)2024

Diagnostic modalities in the mediastinum and the role of bronchoscopy in mediastinal assessment: a narrative review.

Yonatan Dollin, Jorge A Munoz Pineda, Lily Sung, Farnaz Hasteh, Monica Fortich, Amanda Lopez, Keriann Van Nostrand, Niral M Patel, Russell Miller, George Cheng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Mediastinum (Hong Kong, China), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yonatan DollinDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0000-0001-8754-1800
Jorge A Munoz PinedaDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0009-0007-6664-8765
Lily SungDepartement of Radiology, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0009-0002-3439-3490
Farnaz HastehDivision of Pathology, University of California San Diego, San Diego, CA, USA.
Monica FortichDivision of Internal Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0009-0007-7309-1889
Amanda LopezDivision of Internal Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0009-0009-1894-4847
Keriann Van NostrandDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0009-0002-8388-355X
Niral M PatelDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0000-0003-1360-2767
Russell MillerDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0000-0002-4690-4748
George ChengDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA, USA.ORCID https://orcid.org/0000-0001-6859-8705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Diagnosis of pathology in the mediastinum has proven quite challenging, given the wide variability of both benign and malignant diseases that affect a diverse array of structures. This complexity has led to the development of many different non-invasive and invasive diagnostic modalities. Historically, diagnosis of the mediastinum has relied on different imaging modalities such as chest X-ray, computed tomography (CT), magnetic resonance imaging, and positron emission topography. Once a suspicious lesion was identified with one of these techniques, the gold standard for diagnosis was mediastinoscopy for diagnosis and staging of disease. More recently, many minimally invasive techniques such as CT-guided biopsy, endobronchial ultrasound with transbronchial needle aspiration, and endoscopic ultrasound with fine needle aspiration have revolutionized the diagnosis of the mediastinum. This review provides a comprehensive analysis of all the modalities available for diagnosing mediastinal disease with an emphasis on bronchoscopic techniques. Methods: Literature search was performed via the PubMed database. We included all types of articles and study designs, including original research, meta-analyses, reviews, and abstracts. Key Content and Findings: Minimally invasive techniques such as endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound-fine needle aspiration (EUS-FNA) have demonstrated high diagnostic yield and low complication rate and have made a significant difference in the time to diagnosis and lives of patients. There continues to be innovation in the field of bronchoscopy with the development of new technologies such as confocal laser endomicroscopy, optical coherence tomography, and artificial intelligence. Conclusions: Bronchoscopy is and will continue to be an integral modality in minimally invasive diagnosis of the mediastinum.

Indexed as

Endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA)endoscopic ultrasound-fine needle aspiration (EUS-FNA)mediastinal bronchoscopymediastinal modalities

Identifiers

PMID39781205
PMCPMC11707438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.