ArticleCureus2024
Bilateral Ovarian Agenesis and Bone Modeling Disease in Pre-puberty Girl With Primary Amenorrhea.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Impact of Congenital Anomalies of the Male and Female Reproductive Organs on Infertility and Recurrent Pregnancy Loss: A Review.Medicina (Kaunas, Lithuania) · 2026Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ovarian agenesis (OA) is a rare congenital condition characterized by the absence of one or both ovaries, often associated with chromosomal abnormalities, hormonal imbalances, and structural deformities. The condition is frequently diagnosed in females presenting with primary amenorrhea and delayed sexual development. This case report highlights a unique presentation of bilateral ovarian agenesis in a patient with chromosome X translocation, bone modeling disease, and primary amenorrhea. A 17-year-old female with primary amenorrhea and a Madelung deformity presented with wrist pain, paresthesia, and limited range of motion. Imaging revealed delayed joint growth, a fragility fracture, and osteoporosis. Further evaluation uncovered a small uterus and absent ovaries on ultrasound and magnetic resonance imaging (MRI). Hormonal analysis showed elevated gonadotropins, follicle stimulation hormone and luteinizing hormone (FSH and LH), low estradiol, and low anti-mullerian hormone (AMH) levels. Laparoscopy confirmed rudimentary bilateral ovaries and chromosomal analysis revealed 46,X,der(X)t(X;3)(p11;p11), indicating an X chromosome translocation with an
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Registered trials
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