Evidence map›Paper›PMID 39781133›Full record

ArticleCureus2024

Efficacy of Cetylpyridinium Chloride Mouthwash on Denture Plaque Reduction and Microbiome Alteration in a Randomized Crossover Trial.

Hiroko Tahara, Minoru Sanda, Momoe Itsumi, Haruka Fukamachi, Hiromi Nishi, Fuminori Iwasa, Hirotaka Kuwata, Kazuyoshi Baba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiroko TaharaDepartment of Prosthodontics, Graduate School of Dentistry, Showa University, Tokyo, JPN.
Minoru SandaDepartment of Prosthodontics, Graduate School of Dentistry, Showa University, Tokyo, JPN.
Momoe ItsumiDepartment of Oral Microbiology and Immunology, Graduate School of Dentistry, Showa University, Tokyo, JPN.
Haruka FukamachiDepartment of Oral Microbiology and Immunology, Graduate School of Dentistry, Showa University, Tokyo, JPN.
Hiromi NishiDepartment of General Dentistry, Hiroshima University Hospital, Hiroshima, JPN.
Fuminori IwasaDivision of Fixed Prosthodontics, Department of Restorative and Biomaterials Sciences, Meikai University School of Dentistry, Saitama, JPN.
Hirotaka KuwataDepartment of Oral Microbiology and Immunology, Graduate School of Dentistry, Showa University, Tokyo, JPN.
Kazuyoshi BabaDepartment of Prosthodontics, Graduate School of Dentistry, Showa University, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose This study aimed to evaluate the effectiveness of cetylpyridinium chloride (CPC) mouthwash in reducing denture plaque and its impact on the microbial composition of denture plaque. Materials and methods A randomized, placebo-controlled crossover trial included 29 participants with maxillary complete dentures. Participants used either CPC or a placebo mouthwash for one week each in a crossover design. The denture plaque area was quantified using image analysis, and microbiome composition was analyzed via 16S rRNA gene sequencing. Results The use of CPC mouthwash significantly reduced the denture plaque area compared to placebo (p<0.025). Microbiome analysis revealed a significant decrease in the relative abundance of the genus

Indexed as

cetylpyridinium chloridedenture plaquehomeostasismicrobiomeoral hygiene

Identifiers

PMID39781133
PMCPMC11707634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.