Evidence map›Paper›PMID 39780960›Full record

ArticleBiomaterials research2025

Functionalized Periosteum-Derived Microsphere-Hydrogel with Sequential Release of E7 Short Peptide/miR217 for Large Bone Defect Repairing.

Jun Yao, Dan Zu, Qi Dong, Jiajie Xia, Xiaonan Wang, Jingjing Guo, Gaoxiang Ma, Bing Wu, Bin Fang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jun YaoDepartment of Orthopedic Surgery, Shaoxing Central Hospital, The Central Affiliated Hospital, Shaoxing University, Shaoxing 312030, China.
Dan ZuSchool of Life Sciences, Tianjin University, Tianjin 300100, China.
Qi DongDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Jiajie XiaDepartment of Neurosurgery, Shaoxing Central Hospital, The Central Affiliated Hospital, Shaoxing University, Shaoxing 312030, China.
Xiaonan WangDepartment of Pharmacy, Shaoxing Central Hospital, The Central Affiliated Hospital, Shaoxing University, Shaoxing 312030, China.
Jingjing GuoDepartment of Pharmacy, Shaoxing Central Hospital, The Central Affiliated Hospital, Shaoxing University, Shaoxing 312030, China.
Gaoxiang MaDepartment of Orthopedic Surgery, Shaoxing Central Hospital, The Central Affiliated Hospital, Shaoxing University, Shaoxing 312030, China.
Bing WuDepartment of Orthopedic Surgery, Shaoxing Central Hospital, The Central Affiliated Hospital, Shaoxing University, Shaoxing 312030, China.
Bin FangDepartment of Orthopedics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310000, China.ORCID https://orcid.org/0000-0002-7390-5025

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large bone defects are still a persistent challenge in orthopedics. The availability limitations and associated complications of autologous and allogeneic bone have prompted an increasing reliance on tissue engineering and regenerative medicine. In this study, we developed an injectable scaffold combining an acellular extracellular periosteal matrix hydrogel with poly(d,l-lactate-

Identifiers

PMID39780960
PMCPMC11704090

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.