A fast and responsive turn-on fluorescent probe based on a quinone conjugated alkoxy derivative for biothiols and a cellular imaging study.

Ulviyye Nemetova, Ayşe Nur Önem, Alev Er, Sefa Çelik, Ayşen E Özel, Sevim Akyüz, Mustafa Özyürek, Sibel Şahinler Ayla

Abstract read

In one paragraph

Article in Turkish journal of chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ulviyye NemetovaDivision of Organic Chemistry, Department of Chemistry, Faculty of Engineering, İstanbul University-Cerrahpaşa, İstanbul, Turkiye.ORCID https://orcid.org/0000-0003-1038-5074

Ayşe Nur ÖnemDivision of Analytical Chemistry, Department of Chemistry, Faculty of Engineering, İstanbul University-Cerrahpaşa, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-6201-6740

Alev ErDepartment of Physics, Faculty of Science, İstanbul University, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-3190-5342

Sefa ÇelikDepartment of Physics, Faculty of Science, İstanbul University, İstanbul, Turkiye.ORCID https://orcid.org/0000-0001-6216-1297

Ayşen E ÖzelDepartment of Physics, Faculty of Science, İstanbul University, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-8680-8830

Sevim AkyüzDepartment of Physics, Faculty of Science and Letters, İstanbul Kültür University, İstanbul, Turkiye.ORCID https://orcid.org/0000-0003-3313-6927

Mustafa ÖzyürekDivision of Analytical Chemistry, Department of Chemistry, Faculty of Engineering, İstanbul University-Cerrahpaşa, İstanbul, Turkiye.ORCID https://orcid.org/0000-0001-5426-9775

Sibel Şahinler AylaDivision of Organic Chemistry, Department of Chemistry, Faculty of Engineering, İstanbul University-Cerrahpaşa, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-1332-1968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of intracellular biothiols (cysteine, N-acetyl cysteine, and glutathione) with high selectivity and sensitivity is important to reveal biological functions. In this study, a 2-(2-methoxy-4-methylphenoxy)-3-chloro-5,8-dihydroxynaphthalene-1,4-dione (DDN-O) compound

Indexed as

23-dichloro-54-dione8-dihydroxynaphthalene-1bioimagingBiothiolsfluorogenic probemolecular dockingmolecular modeling

Identifiers

PMID39780844

DOI10.55730/1300-0527.3702

PMCPMC11706294

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.