ArticleJTCVS open2024
Multimodal analgesia with parasternal plane block protocol within an enhanced recovery after cardiac surgery program decreases opioid use.
Article in JTCVS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Postoperative Cognitive Dysfunction and Analgesic Outcomes in Cardiac Surgery: Evaluating the Role of Nerve Block Techniques.The Clinical journal of pain · 2026Review
- Impact of Opioid-Free Anesthesia Combined With Enhanced Recovery After Surgery Protocol on Postoperative Recovery Quality in Patients Undergoing Laparoscopic Total Hysterectomy.The journal of obstetrics and gynaecology research · 2026Article
- Intravenous Lidocaine for Postoperative Pain and Recovery After Robotic Prostate Adenomectomy: A Retrospective Observational Cohort Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Different titration protocols in pain management after radical gastrectomy for gastric cancer patients.World journal of gastrointestinal oncology · 2025Article
- New Clinical Advances in Minimally Invasive Coronary Surgery.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study investigated the efficacy of a multimodal analgesia (MMA) with an opioid-sparing strategy, incorporating a parasternal plane block (PPB) within a systematic standardized Enhanced Recovery After Surgery (ERAS) program for patients undergoing elective cardiac surgery. Methods: From 2015 to 2021, 3153 patients underwent elective coronary artery bypass grafting and/or valve procedures. Patients were dichotomized by the presence or absence of an ERAS program including a perioperative MMA with an opioid-sparing approach and PPB protocols. Propensity score matching yielded 1026 well-matched pairs. The primary outcomes were the opioid-free rate and the opioid consumption in morphine milligram equivalents (MME) in the intensive care unit (ICU). The secondary outcomes were postoperative visual analog scale (VAS) scores, mechanical ventilation duration, ileus, delirium, bronchopneumonia, and length of ICU stay. Results: The ICU opioid-free rate was significantly increased in the ERAS group (94.0%) compared with the control group (19.9%; Conclusions: Within a systematic, standardized ERAS program, MMA with an opioid-sparing strategy and PPB enables opioid-free analgesia in the majority of patients, significantly decreases opioid consumption, and ensures effective postoperative pain management, thereby improving outcomes.
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