Evidence map›Paper›PMID 39780805›Full record

ArticleJTCVS open2024

Significant reduction in blood product usage, same early outcomes: Blood conservation in infants undergoing open heart surgery.

Lyubomyr Bohuta, Titus Chan, Kevin Charette, Gregory Latham, Christina L Greene, David Mauchley, Andrew Koth, D Michael McMullan

Abstract read
In one paragraph

Article in JTCVS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lyubomyr BohutaDivision of Cardiac Surgery, Seattle Children's Hospital, Seattle, Wash.
Titus ChanDivision of Critical Care, Seattle Children's Hospital, Seattle, Wash.
Kevin CharettePerfusion Services, Seattle Children's Hospital, Seattle, Wash.
Gregory LathamDivision of Anesthesia, Seattle Children's Hospital, Seattle, Wash.
Christina L GreeneDivision of Cardiac Surgery, Seattle Children's Hospital, Seattle, Wash.
David MauchleyDivision of Cardiac Surgery, Seattle Children's Hospital, Seattle, Wash.
Andrew KothDivision of Critical Care, Seattle Children's Hospital, Seattle, Wash.
D Michael McMullanDivision of Cardiac Surgery, Seattle Children's Hospital, Seattle, Wash.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effect of a blood conservation program on trends in use of donor blood products and early clinical outcomes in infants undergoing open heart surgery. Methods: Four hundred nine patients younger than age 1 year undergoing open-heart surgery between October 1, 2020, and June 30, 2023, were reviewed. The study period was divided into 4 eras with the first era as a before blood conservation baseline using traditional blood management. The following 3 eras comprised incremental implementation and evolution of blood conservation strategies. The total volume of blood products transfused for each surgical hospitalization was calculated and indexed to body weight at time of surgery. Results: There was no significant difference in age at surgery, body weight, distribution of The Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery categories, and in postoperative length of mechanical ventilation, intensive care unit or hospital length of stay, or postoperative mortality ( Conclusions: Blood conservation is associated with significant reduction in usage of blood products during open heart surgery in infants with no significant effect on early outcomes. This trend is observed across all categories of surgical complexity. Additional studies are needed to prove consistency and to determine the longer-term clinical impact of this strategy.

Indexed as

blood conservationcardiopulmonary bypassinfants

Identifiers

PMID39780805
PMCPMC11704574

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.