Evidence map›Paper›PMID 39780798›Full record

ArticleJTCVS open2024

Mitral valve replacement versus repair for severe mitral regurgitation in patients with reduced left ventricular ejection fraction.

Zara Dietze, Mateo Marin-Cuartas, Livia Berkei, Manuela De La Cuesta, Wolfgang Otto, Bettina Pfannmüller, Philipp Kiefer, Martin Misfeld, Alexey Dashkevich, Jagdip Kang and 4 more

Abstract read
In one paragraph

Article in JTCVS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zara DietzeUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Mateo Marin-CuartasUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Livia BerkeiUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Manuela De La CuestaUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Wolfgang OttoUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Bettina PfannmüllerUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Philipp KieferUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Martin MisfeldUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Alexey DashkevichUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Jagdip KangUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Sergey LeontyevUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Michael A BorgerUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Thilo NoackUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Marcel VollrothUniversity Department of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study compares early and long-term outcomes following mitral valve (MV) repair and replacement in patients with mitral regurgitation (MR) and reduced left ventricular ejection fraction (LVEF). Methods: Patients with primary or secondary MR and LVEF <50% who underwent MV replacement or repair (with/without atrial septal defect closure and/or atrial fibrillation ablation) between 2005 and 2017 at our center were retrospectively analyzed using unadjusted and propensity score matching techniques (42 pairs). Results: A total of 356 patients with either primary (n = 162 [45.5%]) or secondary MR (n = 194 [54.5%]) and LVEF <50% underwent MV repair (n = 293 [82.3%]) or replacement (n = 63 [17.7%]) during the study period. In-hospital mortality was 0.3% (repair) and 1.6% (replacement) in the unmatched cohort ( Conclusions: MV repair performed in primary or secondary MR and reduced LVEF provides superior long-term results compared with replacement. Severe LV dysfunction is a significant predictor of reduced survival following MV surgery.

Indexed as

heart failuremitral regurgitationmitral valve repairmitral valve replacement

Identifiers

PMID39780798
PMCPMC11704591

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.