ArticleJournal of orthopaedic surgery and research2025
Diagnostic efficacy of dual-energy CT virtual non-calcium technique in the diagnosis of bone marrow edema of sacroiliac joints in ankylosing spondylitis.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Diagnostic Accuracy of Dual Energy CT for Bone Marrow Edema of the Sacroiliac Joints Compared with MRI: A Systematic Review.Journal of clinical medicine · 2026Review
- Diagnostic Value of T2 Mapping in Sacroiliitis Associated with Spondyloarthropathy.Diagnostics (Basel, Switzerland) · 2025Article
- Dual-Energy Computed Tomography for the Detection of Bone Edema-Like Lesions in the Equine Foot: Standing Horses and Cadaveric Specimens.Veterinary sciences · 2025Article
- Diagnostic accuracy of virtual non-calcium dual-energy computed tomography in the detection of acute occult ankle and calcaneus fractures.Quantitative imaging in medicine and surgery · 2025Article
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Abstract
objectiveIn-depth investigation of the diagnostic performance of dual-energy CT (DECT) virtual non-calcium (VNCa) technique for sacroiliac joint bone marrow edema (BME) in patients with ankylosing spondylitis(AS).
methodsA total of 42 patients with AS)who underwent sacroiliac joint MRI and DECT scans on the same day at our Rheumatology and Immunology Department between August 2022 and June 2023 were selected. Using MRI as the reference standard, the presence of BME on the iliac and sacral surfaces was evaluated, resulting in the categorization of patients into BME-positive and BME-negative groups. Subsequently, the DECT scan data was processed using the "Bone Marrow" algorithm to generate VNCa color-coded images of the bone marrow. The diagnostic performance of DECT in detecting BME was assessed through visual qualitative evaluation and objective quantitative analysis.
resultsVisual qualitative assessment analysis showed good agreement between the results of BME analysis on virtual non-calcium images and MRI images by both physicians (Kappa > 0.61). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of visual qualitative assessment for BME by Physicians A and B were as follows: iliac facet [(92.5%, 88.6%, 88.1%, 92.9%, 90.5%), (90.0%, 90.9%, 90.0%, 90.9%, 90.5%)], sacral facet [(88.4%, 87.8%, 88.4%, 87.8%, 88.1%), (90.7%, 85.3%, 86.7%, 89.7%, 88.1%)].In terms of objective quantitative analysis, the CT values of the edematous areas on the iliac and sacral surfaces were (-41.4 ± 15.9) Hu and (-38.8 ± 19.7) Hu, respectively, while the CT values of normal bone marrow areas were (-79.6 ± 18.2) Hu and (-72.8 ± 14.8) Hu, respectively. The CT values of the edematous areas were higher than those of the non-edematous areas. Based on the receiver operating characteristic curve analysis, the area under the curve for the iliac and sacral surfaces were 0.90 and 0.89, respectively. The optimal CT cutoff values were - 57.4 Hu and - 56.8 Hu, with corresponding sensitivities of 92.5% and 86.4% and specificities of 90.7% and 87.8%.
conclusionThe DECT VNCa technique has a high diagnostic efficacy in the diagnosis of BME in the sacroiliac joints in ankylosing spondylitis in terms of visual qualitative assessment and objective quantitative analysis.
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