SynthesisBMC oral health2025
Incidence of postoperative pain after single-visit and multiple-visit root canal therapy: a systematic review.
Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07064083 (The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain: A Randomized Controlled Clinical Trial
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effectiveness of Ketorolac in Relieving Pain Associated With Root Canal Therapy: A Systematic Review and Meta-Analysis.Clinical and experimental dental research · 2026Pooled it
- The Impact of Different Final Irrigation Activation Techniques on Postoperative Pain in Single Rooted Mandibular Premolar Teeth: Randomised Clinical Trial.European endodontic journal · 2025Trial
- Influence of occlusal reduction on postoperative pain following single-visit root canal treatment in mandibular molars: a randomized controlled trial.Restorative dentistry & endodontics · 2026Article
- Comparative evaluation of chitosan nanoparticles and ethylenediaminetetraacetic acid as intracanal irrigants and their effect on postoperative pain reduction in single-sitting root canal treatment - A randomized controlled trial.Journal of conservative dentistry and endodontics · 2026Article
- Evaluation of Single-Visit Post-endodontic Discomfort Using Three Different Rotary File Systems: An In Vivo Study.Cureus · 2026Article
- Comparative Evaluation of Pain Perception and Postoperative Pain in Children with Precooled Injection Sites Using Popsicles for Local Anesthesia: A Randomized Controlled Trial.International journal of clinical pediatric dentistry · 2026Article
- Post-operative pain in molar teeth with symptomatic apical periodontitis using cryotreated neem extract and cryotreated 2.5% sodium hypochlorite: A randomised double-blinded clinical trial.Bioinformation · 2026Article
- Comparison of post-operative pain between rotary and reciprocating file systems in root canal therapy: AnBioinformation · 2026Article
- Single-visit versus two-visit endodontic treatment for postoperative pain in asymptomatic non-vital mandibular premolars.Bioinformation · 2026Article
- Randomized Trial of Bioceramic Apical Barrier Methods in Necrotic Immature Incisors: Effects on Pain, Extrusion, and Procedure Duration.Children (Basel, Switzerland) · 2025Article
- Clinical Efficacy of Er,Cr:YSGG Laser for Deepithelialization of Free Gingival Grafts in Gingival Recession Treatment: A Randomized, Split-Mouth Clinical Trial.Journal of clinical medicine · 2025Article
- Analysis of postoperative pain after single versus multiple-visit root canal treatment in molars.Bioinformation · 2025Article
- Comparative evaluation of post-operative pain following single vs. multiple visit pulpectomy: A clinical assessment.Bioinformation · 2025Article
- Comparison of the Effectiveness of Single-Visit and Multi-Visit Root Canal Treatment on Healing Intraoral Sinus Tract.International journal of dentistry · 2025Article
- Postoperative pain after single and multiple visits for root canal therapy in necrotic teeth.Bioinformation · 2025Article
- Evidence synthesis of postoperative pain with bioceramic vs. epoxy resin sealers: umbrella review of randomized trials within existing systematic reviews.Frontiers in dental medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIM- The objective of the systematic review is to evaluate the incidence of postoperative pain after single-visit and multiple-visit root canal therapy. METHODS- Published research indexed in PubMed or Scopus or Cochrane or DOAJ or Web of Science evaluating the frequency percentage of postoperative aching after one and several root canal therapy appointments through randomized controlled trials or prospectively were included. RESULT- Most surveys utilized VAS (Visual Analogue Scale) to estimate the degree of pain among the participants. The majority of the studies (n-8) showed no difference between postoperative pain during single-sitting endodontic treatment or multiple-sitting endodontic treatment. On the contrary, several studies (n-6) also revealed that post-obturation pain in a single-appointment root canal therapy is less compared to multi-visit root canal therapy. The current research results give insight into the incidence of postoperative endodontic pain among the study participants undergoing root canal treatment through single or multiple visit appointments. CONCLUSION- The lack of consistency between studies is due to the different ways in which pain intensity is measured and differences in treatment methods, patient selection and treatment outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.