ArticleBMC public health2025
Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Food insecurity and its contributing factors among people living with HIV attending antiretroviral therapy in Addis Ababa, Ethiopia: a mixed-methods study.BMC nutrition · 2026Article
- Perspectives on the Impacts of a Food Support Program on the Well-Being of People Living With HIV (PLHIV) and on Antiretroviral Therapy (ART) in Khomas Region, Namibia.AIDS research and treatment · 2026Article
- Intestinal microecology: a crucial factor influencing incomplete immune reconstitution after antiretroviral therapy in people living with HIV-1.Frontiers in public health · 2026Review
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8 authors.
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Abstract
backgroundDespite advancements in Human Immunodeficiency Virus (HIV) treatment and care, undernutrition remains a significant concern, accelerating disease progression and risk of Acquired Immune Deficiency Syndrome (AIDS)-related deaths. The nutritional status of second-line antiretroviral treatment (SLART) users in Ethiopia has not been thoroughly investigated. So, this study aimed to assess the nutritional status of HIV/AIDS patients who were on SLART and its associated factors in Northern Ethiopia.
methodsA retrospective cross-sectional study was conducted on 366 HIV-infected adults who had been on SLART for at least six months in northern Ethiopia. Clients who had documented Weight and height at six months of therapy were included. Data was entered and cleaned by using EpiDATA version 4.6.0.2 and statistical analysis was done by STATA version 17. Multiple imputation method was applied to manage variables having up to 25% missing values by using R-Version 3.6.2 software. Binary logistic regression was used with P < 0.05 as a significant predictor in the final analysis. Data was collected from February 01 to April 30, 2021.
resultsThe magnitude of undernutrition among adults who were on SLART in the study area was 38.52% (95%CI: 33.65-43.64). Those populations also had a baseline undernutrition status of 39.1% (95%CI: 34.11-44.15) during their transition to SLART. The risk of being malnourished at six months of SLART initiation was fifteen times higher among those who were undernourished at SLART start (AOR:15.099, 95%CI: 8.532, 26.720) reflecting the high burden of the problem in the advanced courses of HIV/AIDS treatment and care.
conclusionsThe proportion of undernutrition among SLART users in Northern Ethiopia is high. During HIV therapy, a client's overall nutritional health is predicted by their prior undernutrition condition. This highlights the need for comprehensive nutritional assessment, counseling, and monitoring of the nutritional status of SLART users in the area with emphasis on an early identification of possible barriers to the improvement of such conditions. Promoting the consumption of nutrient-dense local foods and appropriate food preparation methods in addition to nutritional support are vital in this setting.
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