Evidence map›Paper›PMID 39780094›Full record

ArticleBMC psychiatry2025

A network analysis of depression and anxiety symptoms among Chinese elderly living alone: based on the 2017-2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS).

Ze Chang, Yunfan Zhang, Xiao Liang, Yunmeng Chen, Chunyan Guo, Xiansu Chi, Liuding Wang, Xie Wang, Hong Chen, Zixuan Zhang and 3 more

Abstract read
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

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0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ze Chang *Xiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Yunfan Zhang *Xiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Xiao LiangXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Yunmeng ChenXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Chunyan GuoXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Xiansu ChiXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Liuding WangXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Xie WangThe First Affiliated Hospital of Anhui, University of Traditional Chinese Medicine, Hefei, 230031, China.
Hong ChenThe First Affiliated Hospital of Anhui, University of Traditional Chinese Medicine, Hefei, 230031, China.
Zixuan ZhangXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Longtao LiuXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Lina MiaoXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China. 18811367899@163.com.
Yunling ZhangXiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China. yunlingzhang2004@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly individuals living alone represent a vulnerable group with limited family support, making them more susceptible to mental health issues such as depression and anxiety. This study aims to construct a network model of depression and anxiety symptoms among older adults living alone, exploring the correlations and centrality of different symptoms. The goal is to identify core and bridging symptoms to inform clinical interventions.

methodsUsing data from the 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS), this study constructed a network model of depression and anxiety symptoms among elderly individuals living alone. Depression and anxiety symptoms were assessed using the Center for Epidemiologic Studies Depression Scale-10 (CESD-10) and the Generalized Anxiety Disorder Scale-7 (GAD-7), respectively. A Gaussian Graphical Model (GGM) was employed to build the symptom network, and the Fruchterman-Reingold algorithm was used for visualization, with the thickness and color of the edges representing partial correlations between symptoms. To minimize spurious correlations, the Least Absolute Shrinkage and Selection Operator (LASSO) method was applied for regularization, and the optimal regularization parameters were selected using the Extended Bayesian Information Criterion (EBIC). We further calculated Expected Influence (EI) and Bridge Expected Influence (Bridge EI) to evaluate the importance of symptoms. Non-parametric bootstrap methods were used to assess the stability and accuracy of the network.

resultsThe Network centrality analysis revealed that GAD2 (Uncontrollable worry) and GAD4 (Trouble relaxing) exhibited the highest strength centrality (1.128 and 1.102, respectively), indicating their significant direct associations with other symptoms and their roles as core nodes in the anxiety symptom network. Other highly central nodes, such as GAD1 (Nervousness or anxiety) and GAD3 (Generalized worry), further underscore the dominance of anxiety symptoms in the overall network. Betweenness centrality results highlighted GAD1 (Nervousness or anxiety) and GAD2 (Uncontrollable worry) as critical bridge nodes facilitating information flow between different symptoms, while CESD3 (Feeling depressed) demonstrated a bridging role across modules. Weighted analyses further confirmed the central importance of GAD2 (Uncontrollable worry) and GAD4 (Trouble relaxing). Additionally, the analysis showed gender differences in the depression-anxiety networks of elderly individuals living alone.

conclusionThis study, through network analysis, uncovered the complex relationships between depression and anxiety symptoms among elderly individuals living alone, identifying GAD2 (Uncontrollable worry) and GAD4 (Trouble relaxing) as core symptoms. These findings provide essential insights for targeted interventions. Future research should explore intervention strategies for these symptoms to improve the mental health of elderly individuals living alone.

Indexed as

AnxietyDepressionAgedAged, 80 and overBayes TheoremChinaEast Asian PeopleFemaleHealth SurveysHumansLongevityLongitudinal StudiesMaleCore symptomsDepression and anxietyElderly living aloneNetwork analysis

Identifiers

PMID39780094
PMCPMC11716466

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.