Evidence map›Paper›PMID 39780085›Full record

ArticleBMC public health2025

Cardiovascular mortality risk among small bowel adenocarcinoma patients: a population-based study.

Yao Zhang, Shicong Zeng, Zongwen Wang, Qiankun Zhu, Jingtao Li, Xiaohang Ren, Shuoheng Ma, Gang Tan, Bo Zhai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yao ZhangDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.ORCID 0000-0002-9343-6238
Shicong ZengDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Zongwen WangDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Qiankun ZhuDepartment of Intervention Radiology, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Jingtao LiDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Xiaohang RenDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Shuoheng MaDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China.
Gang TanDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China. tangang@hrbmu.edu.cn.ORCID 0000-0001-8096-4798
Bo ZhaiDepartment of General Surgery, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150001, China. zhaibo@hrbmu.edu.cn.ORCID 0000-0002-8671-261X

Funding

The Medical Research Projects of Health Commission of Heilongjiang Province no. 20220404011082
6 · The paper itself

Abstract

backgroundThe objective of this research is to statistically assess the risk of cardiovascular mortality (CVM) between patients with small bowel adenocarcinoma (SBA) and the general population. Additionally, it aims to identify CVM-associated risk factors among individuals with SBA.

methodsData obtained between 2000 and 2017 on SBA patients from the Surveillance, Epidemiology, and End Results (SEER) database were examined. Standardized mortality ratios (SMRs) and absolute excess risks (AERs) were obtained to compare CVM between patients and the general US population. To evaluate the cumulative mortality (CM) rate for all causes of death (COD), cumulative hazard curves were constructed. Two multivariate competing risk models were established to determine the independent predictors for CVM.

resultsIn the cohort of 5,175 SBA patients observed for 15,068.24 person-years, a total of 205 deaths were attributed to cardiovascular disease (CVD). The overall SMR of CVM was 1.41 (95% confidence interval (CI): 1.23-1.62, P < 0.05), whereas it reached 2.99 during the early stage of latency. Additionally, independent risk factors for CVM included age, marital status, calendar year of diagnosis, disease differentiation degree, SEER stage, and chemotherapy status.

conclusionsSBA patients exhibited a substantially elevated risk of developing CVM compared to the general US population. During the follow-up period, the CM rate for CVM continued to rise steadily. Timely identification of high-risk groups and effective interventions to safeguard cardiovascular health significantly improve patient prognosis.

Indexed as

AdenocarcinomaCardiovascular DiseasesIntestinal NeoplasmsIntestine, SmallSEER ProgramAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsUnited StatesCardiovascular mortalityClinical cancer researchCompeting risk regressionEpidemiologySmall bowel adenocarcinoma

Identifiers

PMID39780085
PMCPMC11715972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.