ArticleNature chemistry2025
A pseudo-cubic metal-organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation.
Article in Nature chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Self-Healing Pd(II) Cage Metallogels for Iodine Capture in Water and Heterogeneous Photocatalysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Phase-dependent responsiveness in soft porous crystals assembled from flexible metal-organic cages.Chemical science · 2026Article
- Rationalizing Guest-Driven Cooperative Effect in a Hierarchical Host-Guest Aqueous Assembly.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Adaptive Cavity-Enabled Crystalline Chirality in Nanocarbon Cages.Angewandte Chemie (International ed. in English) · 2026Article
- Article
- London Dispersion Governs Stereochemistry, Stability, and Self-Sorting in a System of MJournal of the American Chemical Society · 2026Article
- Peptide cages: bioinspired supramolecular architectures for next-generation applications.Chemical science · 2026Review
- A state-switchable TADF macrocycle for multi-analyte sensing and hydrogen gas-driven emission enhancement.Communications chemistry · 2026Article
- Light-Induced Rotation of a Molecular Motor in the Confined Space of a Metal-Organic Nanocage.Journal of the American Chemical Society · 2026Article
- Conformational adaptability enabled higher-order self-sorting processes in coordination cages.Chemical science · 2026Article
- Hierarchical assembly of a TiNature communications · 2026Article
- Structural Interconversions and Guest Binding Properties of Tetrakis(formylpyridine)-BasedJournal of the American Chemical Society · 2025Article
- Tautomerism-Coupled Self-Assembly and Transformations of Iminopyrrole Metallacages.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Hosting of [Cs(crown ether)Chemical science · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The creation of hosts capable of accommodating different guest molecules may enable these hosts to play useful roles in chemical purifications, among other applications. Metal-organic cages are excellent hosts for various guests, but they generally incorporate rigid structural units that hinder dynamic adaptation to specific guests. Here we report a conformationally adaptable pseudo-cubic cage that can dynamically increase its cavity volume to fit guests with differing sizes. This pseudo-cube incorporates a tetramine subcomponent with 2,6-naphthalene arms that cooperatively adopt a non-planar conformation, enabling the cage faces to switch between endo and exo states. A wide range of guest molecules were observed to bind within the cavity of this cage, spanning a range of sizes from 46% to 154% of the cavity volume of the empty cage. Experimental and computational evidence characterizes the flipping of cage faces from endo to exo, expanding the cavity upon binding of larger guests.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.