ArticleScientific reports2025
Live birth prevalence of major congenital anomalies in the United Arab Emirates.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity.Journal of biochemical and molecular toxicology · 2026Review
- Patterns and risk factors of birth defects in Bangladesh: evidence from a neonatal intensive care unit.BMC pregnancy and childbirth · 2026Observational
- Article
- A comprehensive survey of congenital malformations in three governorates of Southern Iraq (Basrah, Misan, and Thi Qar), 2020-2023.BMC pregnancy and childbirth · 2025Article
- Prevalence and prenatal diagnosis of major congenital anomalies in Dubai: first insights and emerging patterns in a multicenter cohort study.BMC pregnancy and childbirth · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Major congenital anomalies (MCAs) significantly contribute to perinatal mortality and morbidity. Globally, the United Arab Emirates has the sixth-highest prevalence rate of congenital anomalies. The lack of clear baseline prevalence data for MCAs impedes the development of interventions to alleviate this burden. This study aimed to estimate the live birth prevalence of perinatally diagnosed MCAs in a sample of the Emirati population. The analysis was based on a cohort of all singleton live births in the Mutaba'ah study. Minor anomalies were excluded and the live birth prevalence of MCAs was estimated as the number of affected births per 1000 live births. Among 4034 singleton live births, 284 neonates were diagnosed with at least one MCAs, corresponding to a live birth prevalence of 70.4/1000 live births (95% confidence interval: 62.7-78.7). Of the 284 neonates, 86% presented with single-system anomalies, while 14% displayed multi-system involvement. The circulatory system was predominately affected (21.3/1000), followed by the urinary, genital, and musculoskeletal systems. Within the circulatory system, anomalies of cardiac septa (88.6%) and great arteries (70.2%) were the most prevalent. The findings indicate a relatively high live birth prevalence of MCAs. Further studies are needed to identify risk factors and explore screening and prevention strategies.
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