Evidence map›Paper›PMID 39779853›Full record

ArticleNature2025

Satellite DNA shapes dictate pericentromere packaging in female meiosis.

Damian Dudka, Jennine M Dawicki-McKenna, Xueqi Sun, Keagan Beeravolu, Takashi Akera, Michael A Lampson, Ben E Black

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Cross-species incompatibilities offer new insights into the functional consequences of satellite DNA evolution.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Cytogenomics of Myloplus tiete reveals conserved satellite DNAs since the Late Eocene in Serrasalmidae (Teleostei, Characiformes).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Article
  7. Article
  8. The role of HMGA1 in genome stability: Implications in human cancer.Cellular and molecular life sciences : CMLS · 2026
    Review
  9. Article
  10. Satellite DNA Genomics: The Ongoing Story.International journal of molecular sciences · 2025
    Review
  11. Article
  12. Centromere regulation in the germline and early embryo.Current opinion in genetics & development · 2025
    Review
  13. Article
  14. Article
  15. Centromeres drive and take a break.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Damian DudkaDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
Jennine M Dawicki-McKenna *Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-1293-640X
Xueqi Sun *Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
Keagan BeeravoluDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0009-0009-2273-8835
Takashi AkeraCell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-8406-9333
Michael A LampsonDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA. lampson@sas.upenn.edu.ORCID 0000-0002-2825-1894
Ben E BlackDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. blackbe@pennmedicine.upenn.edu.ORCID 0000-0002-3707-9483

Funding

Cell Biological mechanisms of centromere driveR35GM122475 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Michael Lampson · 2017 to 2026
$4.5M
Centromere identity, strength, and regulationR35GM130302 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ben E. Black · 2019 to 2026
$4.3M
Age and molecular mechanisms contributing to aneuploidy in oocytesR01HD058730 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BLACK, BEN E., LAMPSON, MICHAEL · 2009 to 2020
$3.2M
NICHD NIH HHS R01 HD058730NIGMS NIH HHS R35 GM122475NIGMS NIH HHS R35 GM130302
6 · The paper itself

Abstract

The abundance and sequence of satellite DNA at and around centromeres is evolving rapidly despite the highly conserved and essential process through which the centromere directs chromosome inheritance

Indexed as

CentromereDNA, SatelliteMeiosisNucleic Acid ConformationAnimalsChromosome SegregationFemaleHeterochromatinHMGA1a ProteinKinetochoresMiceMicrotubulesOocytesSpindle ApparatusDNA, SatelliteHeterochromatinHMGA1a Protein

Identifiers

PMID39779853
PMCPMC11880906

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.