Evidence map›Paper›PMID 39779846›Full record

ArticleNature2025

Molecular and cellular dynamics of the developing human neocortex.

Li Wang, Cheng Wang, Juan A Moriano, Songcang Chen, Guolong Zuo, Arantxa Cebrián-Silla, Shaobo Zhang, Tanzila Mukhtar, Shaohui Wang, Mengyi Song and 10 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed.

  1. Human-biasedLife science alliance · 2026
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Li Wang *The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA. Li.Wang@ucsf.edu.ORCID 0000-0001-9510-6294
Cheng Wang *The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Juan A MorianoThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-6781-340X
Songcang ChenThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Guolong ZuoThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-1214-8849
Arantxa Cebrián-SillaThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Shaobo ZhangDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.
Tanzila MukhtarThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Shaohui WangThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Mengyi SongThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Lilian Gomes de OliveiraThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Qiuli BiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Jonathan J AugustinThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Xinxin GeDepartment of Physiology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2961-7760
Mercedes F ParedesThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2503-1447
Eric J HuangThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-5381-3801
Arturo Alvarez-BuyllaThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Xin DuanDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-5260-8972
Jingjing LiThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA. Jingjing.Li@ucsf.edu.ORCID 0000-0001-6025-9522
Arnold R KriegsteinThe Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA. Arnold.Kriegstein@ucsf.edu.ORCID 0000-0001-5742-2990

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GERMAN, MICHAEL S · 2003 to 2019
$21.8M
Regulation of Cellular Pathwaysin Human Brain DevelopmentP01NS083513 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PIAO, XIANHUA · 2014 to 2024
$12.6M
Development and Expansion of the Human Cerebral CortexR35NS097305 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRIEGSTEIN, ARNOLD · 2017 to 2024
$8.5M
A Cellular Resolution Census of the Developing Human BrainU01MH114825 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, ERIC J, KRIEGSTEIN, ARNOLD · 2017 to 2021
$6.7M
MAPPING RETINOTECTAL CIRCUITS FOR VISUAL-EVOKED INNATE BEHAVIORSR01NS123912 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DUAN, XIN, SCANZIANI, MASSIMO · 2021 to 2025
$3.6M
Mechanisms Underlying Type II Cadherin Guided Assembly of Retinal CircuitsR01EY030138 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Xin Duan · 2020 to 2026
$3.2M
Developmental Topology of the Human Cerebral CortexR35NS137344 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ARNOLD KRIEGSTEIN · 2025 to 2026
$2.1M
Single-Cell Analysis of the Noncoding Genome in Human Diseases and EvolutionR35GM142983 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LI, JINGJING · 2021 to 2025
$2.0M
Illumina NovaSeq 6000 Sequencing SystemS10OD028511 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOW, ERIC D · 2020 to 2020
$583k
BD FACSAria Fusion Cell SorterS10OD021822 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, MICHAEL R. · 2016 to 2016
$573k
Identifying mechanisms ofsynapse maturation at neuronal subtype resolutionK99MH131832 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, LI · 2023 to 2024
$182k
NEI NIH HHS R01 EY030138NIDDK NIH HHS P30 DK063720NIGMS NIH HHS R35 GM142983NIH HHS S10 OD021822NIH HHS S10 OD028511NIMH NIH HHS K99 MH131832NIMH NIH HHS U01 MH114825NINDS NIH HHS P01 NS083513NINDS NIH HHS R01 NS123912NINDS NIH HHS R35 NS097305NINDS NIH HHS R35 NS137344
6 · The paper itself

Abstract

The development of the human neocortex is highly dynamic, involving complex cellular trajectories controlled by gene regulation

Indexed as

NeocortexAdolescentAstrocytesAutism Spectrum DisorderCell LineageChildChild, PreschoolChromatinFemaleGene Regulatory NetworksGenome-Wide Association StudyGlioblastomaHumansMaleNeural Stem CellsNeurogenesisChromatin

Identifiers

PMID39779846
PMCPMC12589127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.