Evidence map›Paper›PMID 39779831›Full record

ArticleScientific reports2025

Association between allergic diseases and mucosal healing in ulcerative colitis.

Yasunori Yamamoto, Shinya Furukawa, Osamu Yoshida, Teruki Miyake, Kana Shiraishi, Yu Hashimoto, Kazuhiro Tange, Shogo Kitahata, Tomoyuki Ninomiya, Sen Yagi and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yasunori YamamotoEndoscopy Center, Ehime University Hospital, Toon, Ehime, Japan.
Shinya FurukawaHealth Services Center, Ehime University, Matsuyama, Ehime, 790-8577, Japan. shinya.furukawa@gmail.com.
Osamu YoshidaDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Teruki MiyakeDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Kana ShiraishiDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Yu HashimotoDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Kazuhiro TangeDepartment of Inflammatory Bowel Diseases and Therapeutics, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Shogo KitahataDepartment of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.
Tomoyuki NinomiyaDepartment of Gastroenterology, Ehime Prefectural Central Hospital, Matsuyama, Ehime, Japan.
Sen YagiDepartment of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Ehime, Japan.
Hanayama MasakazuDepartment of Gastroenterology, Matsuyama Shimin Hospital, Matsuyama, Ehime, Japan.
Seiyuu SuzukiDepartment of Gastroenterology, Sumitomo Besshi Hospital, Niihama, Ehime, Japan.
Naozumi ShibataDepartment of Gastroenterology, Ehime Prefectural Niihama Hospital, Niihama, Ehime, Japan.
Hidehiro MurakamiDepartment of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Ehime, Japan.
Katsuhisa OhashiOHASHI Clinic Participate in Gastro-Enterology and Ano-Proctology, Niihama, Ehime, Japan.
Hideomi TomidaEndoscopy Center, Ehime University Hospital, Toon, Ehime, Japan.
Eiji TakeshitaDepartment of Inflammatory Bowel Diseases and Therapeutics, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
Yoshio IkedaEndoscopy Center, Ehime University Hospital, Toon, Ehime, Japan.
Yoichi HiasaDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic diseases and ulcerative colitis (UC) share pathophysiological similarities. This study aimed to investigate the unclear association between allergic diseases and mucosal healing (MH), an important factor in the prognosis of UC. We studied 289 Japanese patients with UC. Information on allergic diseases (bronchial asthma, atopic dermatitis, pollen allergy, food allergy, and drug allergy), as diagnosed by physicians, was collected through self-reported questionnaires. The definition of MH was Mayo Endoscopic Score 0. The association between each allergic disease and its multimorbidity with MH was evaluated using multivariate logistic regression analyses. Pollen allergy was the most common allergic condition (36.3%). Pollen allergy and food allergy were independently associated with MH (pollen allergy adjusted OR: 1.82 [95% CI: 1.01-3.26]; food allergy adjusted OR: 3.47 [95% CI: 1.26-9.68]). The rates of MH for 0 and 3 or more allergic diseases were 24.6% and 4.2%, respectively. After adjustment for confounders, 3 or more allergic diseases were independently associated with MH (adjusted OR: 8.13 [95% CI: 2.17-34.04], p for trend = 0.020). This study demonstrates a significant positive association between specific allergic diseases (pollen and food allergies) and MH in UC patients, with a stronger association in cases of allergic multimorbidity.

Indexed as

Colitis, UlcerativeAdultAgedFemaleFood HypersensitivityHumansHypersensitivityIntestinal MucosaJapanMaleMiddle AgedWound HealingAllergic diseasesAtopic dermatitisFood allergyInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID39779831
PMCPMC11711406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.