Evidence map›Paper›PMID 39779634›Full record

ArticleBreast cancer research and treatment2025

Comparison of survival between unilateral and bilateral breast cancers using propensity score matching: a retrospective single-center analysis.

Talar Ozler, Rusen Cosar, Necdet Sut, Dilek Nurlu, Şule Parlar, Sinan Ateş, Mert Hacı Dertli, Yusuf Kavuzlu, Sekip Kavukcu, Mert Chousein and 5 more

Abstract readComparative Study
In one paragraph

Article in Breast cancer research and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Talar OzlerDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Rusen CosarDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey. rusencosar@trakya.edu.tr.
Necdet SutDepartment of Biostatistics, Faculty of Medicine, Trakya University, Edirne, Turkey.
Dilek NurluDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Şule ParlarDepartment of Medical Physics, Faculty of Medicine, Trakya University, Edirne, Turkey.
Sinan AteşDepartment of Obstetrics and Gynecology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Mert Hacı DertliDepartment of Radiation Oncology, Istanbul Prof. Dr. Cemil Taşçıoğlu City Hospital, Istanbul, Turkey.
Yusuf KavuzluDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Sekip KavukcuDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Mert ChouseinDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Gokay YıldızDepartment of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Nermin TunçbilekDepartment of Radiology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Muhammet Bekir HacıogluDepartment of Medical Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Ebru TastekinDepartment of Pathology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Sernaz TopaloğluDepartment of Medical Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe characteristics of patients with bilateral and unilateral breast cancer at the time of diagnosis or during follow-up have been compared, focusing on the differences in disease-free survival and overall survival between these groups.

methodsA total of 1,947 patients diagnosed with invasive carcinoma were included in the study. 1876 ​​(96.4%) of our patients had unilateral and 71 (3.6%) had bilateral breast cancer. Among the bilateral breast cancer patients n = 47 were metachronous, while n = 24 were synchronous.

resultsSBBC, which had the lowest OS duration, showed a statistically significant difference compared to MBCC, similar to that observed in unilateral breast cancer (p = 0.027).

conclusionThe fact that SBBC has the lowest survival rate despite more aggressive treatments should be considered a poor prognostic factor for survival on its own.

Indexed as

Breast NeoplasmsUnilateral Breast NeoplasmsAdultAgedAged, 80 and overDisease-Free SurvivalFemaleHumansMiddle AgedNeoplasm StagingPrognosisPropensity ScoreRetrospective StudiesBilateral breast cancerBreast CancerMetachronous bilateral breast cancerMultivariate cox regression analysis with backward stepwisePropensity score analysisSynchronous bilateral breast cancerUnilateral breast cancer

Identifiers

PMID39779634
PMCPMC11953229

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.