Evidence map›Paper›PMID 39779215›Full record

Observational studyEndocrine journal2025

Handgrip strength in patients with type 2 diabetes correlates with diabetic polyneuropathy. A single-center, retrospective observational study in Japanese patients.

Yuichiro Iwamoto, Shuhei Nakanishi, Masahiro Komi, Yuto Kimura, Yuki Watanabe, Taku Sasaki, Erina Nakao, Masato Kubo, Toshitomo Sugisaki, Kazunori Dan and 10 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Endocrine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yuichiro IwamotoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.ORCID http://orcid.org/0000-0001-8162-359X
Shuhei NakanishiDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Masahiro KomiDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Yuto KimuraDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Yuki WatanabeDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Taku SasakiDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Erina NakaoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Masato KuboDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Toshitomo SugisakiDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Kazunori DanDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Yui OkamotoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Hideyuki IwamotoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Junpei SanadaDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Yoshiro FushimiDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Yukino KatakuraDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Tomohiko KimuraDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Masashi ShimodaDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Tomoatsu MuneDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Kohei KakuDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.
Hideaki KanetoDepartment of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Okayama 701-0192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nerve conduction studies (NCS) are the standard method for diagnosing diabetic polyneuropathy. Because a clear association between handgrip strength and diabetic neuropathy can serve as a screening tool, the present study evaluated the association between handgrip strength and NCS and diabetes-related complications. A total of 436 patients with type 2 diabetes (T2D) who were admitted to our hospital between April 1, 2018 and March 31, 2023, and evaluated using Baba's diabetic neuropathy classification (BDC) were included. The participants were grouped by sex using the grip strength tertile method to assess correlations with the prevalence of diabetic microvascular complications in the high-handgrip group (HG), middle-handgrip group (MG), and low-handgrip group (LG). The percentage of BDC-0 was 65% in the HG, 54% in the MG, and 36% in the LG. Furthermore, none of the participants in the HG had BDC-3/4, whereas 4% in the MG and 15% in the LG had BDC-3/4. The morbidity progression of diabetic neuropathy was seen in the order of LG, MG, and HG (p < 0.001). Patients with T2D and advanced diabetic neuropathy had decreased handgrip strength. Early evaluation of BDC and other NCS should be considered if decreased handgrip strength is evident.

Indexed as

Diabetes Mellitus, Type 2Diabetic NeuropathiesHand StrengthAgedFemaleHumansJapanMaleMiddle AgedNeural ConductionRetrospective StudiesDiabetic polyneuropathyHandgrip strengthMicrovascular complicationsNerve conduction studyType 2 diabetes

Identifiers

PMID39779215
PMCPMC11997270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.