ArticleCardiology2025
In vivo Predictors of Focal Type In-Stent Restenosis: A Clinical, Angiographical, and Optical Coherence Tomography Study.
Article in Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Practical Management in Coronary In-Stent Restenosis: A Narrative Review.Journal of clinical medicine · 2026Review
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Authors and funding
15 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionFew studies have evaluated different patterns of in-stent restenosis by optical coherence tomography (OCT). This study aimed to identify in vivo predictors for focal restenosis in patients with in-stent restenosis (ISR).
methodsThe study recruited patients with ISR who underwent OCT examination in the Cardiology Department of the Affiliated Hospital of Zunyi Medical University from October 2018 to December 2022. Based on the angiographic classification of ISR lesions, the patients were divided into two groups: the focal group (n = 58) and the non-focal group (n = 158).
resultsThe white blood cell count was higher in the non-focal group than those in focal type (7.8 ± 3.0 vs. 6.6 ± 2.1, p = 0.007). The prevalence of lipid-rich plaque was higher in patients with focal ISR (65.5% vs. 42.4%, p = 0.003). The occurrence of red thrombus (27.8% vs. 12.1%, p = 0.016) and white thrombus (41.1% vs. 24.1%, p = 0.021) was higher in the non-focal group. Multivariate analysis showed that low-density lipoprotein cholesterol C (odds ratio [OR]: 3.341, 95% confidence interval [CI]: 1.714-9.784, p = 0.046) was independently associated with focal restenosis. While white blood cell count (OR: 0.814, 95% CI: 0.657-0.913, p = 0.047) and stent malapposition (OR: 0.228, 95% CI: 0.057-0.896, p = 0.037) were independently associated with non-focal restenosis.
conclusionThere were significant differences in clinical baselines and OCT identified morphological characteristics in patients between focal and non-focal groups. Low-density lipoprotein cholesterol C was independently associated with focal restenosis. White blood cell count and stent malapposition were correlated with non-focal restenosis.
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