Evidence map›Paper›PMID 39777391›Full record

ArticleJournal of conservative dentistry and endodontics2024

"Comparative evaluation of cytotoxicity of three herbal endodontic irrigants at three intervals of time" - An

H Suraksha, Shibani Shetty, K B Jayalakshmi, I Sujatha, S Harishma, Saloni Choudhary

Abstract read
In one paragraph

Article in Journal of conservative dentistry and endodontics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A randomized clinical comparative evaluation of interappointment flare-ups on placingJournal of conservative dentistry and endodontics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

H SurakshaDepartment of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
Shibani ShettyDepartment of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
K B JayalakshmiDepartment of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
I SujathaDepartment of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
S HarishmaDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Rajiv Gandhi Salai, Kelambaakkam, Kancheepuram, Tamil Nadu, India.
Saloni ChoudharyDepartment of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The aim of the study was to evaluate and compare the cytotoxicity of 25% of neem leaf extract ( Methodology: Four groups were formed ( Results: The reduction in the mean Hb values was not statistically significant in the normal saline, guava, and cinnamon groups. However, in the neem extract group, the mean Hb values reduced significantly at Conclusion: In the present study, 20% guava extract had the lowest cytotoxicity and cytotoxicity increased with time. Hence, 20% guava extract can be used as an alternative to conventional irrigants as it has been shown to have the least cytotoxicity.

Indexed as

Azadirachta indicaCinnamomum zeylanicumcytotoxicityherbal endodontic irrigantsPsidium guajava

Identifiers

PMID39777391
PMCPMC11702879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.