Evidence map›Paper›PMID 39777258›Full record

ArticleNeuro-oncology advances

Pediatric brain tumor classification using deep learning on MR images with age fusion.

Iulian Emil Tampu, Tamara Bianchessi, Ida Blystad, Peter Lundberg, Per Nyman, Anders Eklund, Neda Haj-Hosseini

Abstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Explainable AI: Ethical Frameworks, Bias, and the Necessity for Benchmarks.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2026
    Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iulian Emil TampuCenter for Medical Image Science and Visualization, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0002-7582-1706
Tamara BianchessiDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0001-9709-803X
Ida BlystadDepartment of Radiology and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0002-8857-5698
Peter LundbergDepartment of Radiation Physics and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0001-8661-2232
Per NymanCrown Princess Victoria Children's Hospital and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0001-8921-431X
Anders EklundDivision of Statistics & Machine Learning, Department of Computer and Information Science, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0001-7061-7995
Neda Haj-HosseiniCenter for Medical Image Science and Visualization, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0002-0555-8877

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To implement and evaluate deep learning-based methods for the classification of pediatric brain tumors (PBT) in magnetic resonance (MR) data. Methods: A subset of the "Children's Brain Tumor Network" dataset was retrospectively used ( Results: The highest tumor-type classification performance was achieved when using a vision transformer model pre-trained on ImageNet and fine-tuned on ADC images with age fusion (Matthews correlation coefficient [MCC]: 0.77 ± 0.14, Accuracy: 0.87 ± 0.08), followed by models trained on T2w (MCC: 0.58 ± 0.11, Accuracy: 0.73 ± 0.08) and T1w post-contrast (MCC: 0.41 ± 0.11, Accuracy: 0.62 ± 0.08) data. Age fusion marginally improved the model's performance. Both model architectures performed similarly across the experiments, with no differences between the pre-training strategies. Grad-CAMs showed that the models' attention focused on the brain region. PCA of the feature space showed greater separation of the tumor-type clusters when using contrastive pre-training. Conclusion: Classification of PBT on MR images could be accomplished using deep learning, with the top-performing model being trained on ADC data, which radiologists use for the clinical classification of these tumors.

Indexed as

agedata fusiondeep learningMRIpediatric brain tumor

Identifiers

PMID39777258
PMCPMC11701748

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.