Evidence map›Paper›PMID 39777227›Full record

ArticleProceedings of the ... International Brain-Computer Interface Conference2024

AN ONLINE SPIKE DETECTION AND MONITORING FRAMEWORK IN IEEG RECORDED USING BRAIN INTERCHANGE DEVICE.

Behrang Fazli Besheli, Amir Hossein Ayyoubi, Jhan L Okkabaz, Chandra Prakash Swamy, Michael M Quach, Kai J Miller, Gregory A Worrell, Nuri F Ince

Abstract read
In one paragraph

Article in Proceedings of the ... International Brain-Computer Interface Conference, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A RAPID PROTOTYPING ENVIRONMENT FOR CLOSED-LOOP NEUROMODULATION USING THE BRAIN INTERCHANGE SYSTEM.Proceedings of the ... Design of Medical Devices Conference. Design of Medical Devices Conference · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Behrang Fazli BesheliDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Amir Hossein AyyoubiDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Jhan L OkkabazDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Chandra Prakash SwamyDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Michael M QuachDepartment of Neurology, Texas Children's Hospital, Houston, TX, USA.
Kai J MillerDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Gregory A WorrellDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Nuri F InceDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.

Funding

Acute Modulation of Stereotyped High Frequency Oscillations with a Closed-Loop Brain Interchange System in Drug Resistant EpilepsyUH3NS117944 · NINDS · UNIVERSITY OF HOUSTON · PI Nuri Firat Ince · 2021 to 2026
$2.9M
Investigation of Stereotyped High-Frequency Oscillations with Computational Intelligence for the Prediction of Seizure Onset Zone in EpilepsyR01NS112497 · NINDS · UNIVERSITY OF HOUSTON · PI INCE, NURI FIRAT · 2019 to 2023
$2.3M
NINDS NIH HHS R01 NS112497NINDS NIH HHS UH3 NS117944
6 · The paper itself

Abstract

In this study, we developed and validated an online analysis framework in MATLAB Simulink for recording and analysis of intracranial electroencephalography (iEEG). This framework aims to detect interictal spikes in patients with epilepsy as the data is being recorded. An online spike detection was performed over 10-minute interictal iEEG data recorded with Brain Interchange CorTec in three human subjects. A pool of detected spikes is then broadcasted using User Datagram Protocol (UDP) to an external graphical user interface for further post-processing and visualization. The real-time spike detector demonstrated a 99% similarity index with the previously published offline detector, identifying interictal spikes. Furthermore, our findings indicated that channels with highest spike rates, captured with Brain Interchange CorTec, were in the epileptogenic focus. By enabling the detection of interictal spikes in an online fashion, this work provides early feedback on the probable seizure onset zone (SOZ) and suggests a promising direction for enhancing SOZ localization accuracy to clinicians, which is crucial for the surgical treatment of epilepsy.

Identifiers

PMID39777227
PMCPMC11706362

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.