Evidence map›Paper›PMID 39777187›Full record

ReviewSurgical neurology international2024

Demographic and regional patterns of epilepsy-related mortality in the USA: Insights from CDC WONDER data.

Javed Iqbal, Muhammad Ashir Shafique, Burhanuddin Sohail Rangwala, Hafsah Alim Ur Rahman, Muhammad Abdullah Naveed, Afia Fatima, Ahila Ali, Tirath Patel, Moosa Abdur Raqib, Muhammad Saqlain Mustafa and 5 more

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Javed IqbalDepartment of Neurosurgery, King Edward Medical University Pakistan, Lahore, Pakistan.
Muhammad Ashir ShafiqueDepartment of Neurosurgery, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Burhanuddin Sohail RangwalaDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Hafsah Alim Ur RahmanDepartment of Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.
Muhammad Abdullah NaveedDepartment of Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.
Afia FatimaDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Ahila AliDepartment of Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.
Tirath PatelDepartment of Neurosurgery, American University of Antigua, Coolidge, Saint George Parish, Antigua and Barbuda.
Moosa Abdur RaqibDepartment of Medicine, Liaquat College of Medicine and Dentistry, Karachi, Pakistan.
Muhammad Saqlain MustafaDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Abdul HaseebDepartment of Medicine, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Sandesh RajaDepartment of Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.
Adarsh RajaDepartment of Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, Pakistan.
Stephanie HageDepartment of Neurosurgery, University of Chicago, Chicago, United States.
Mohammad AshrafWolfson School of Medicine, University of Glasgow, Scotland, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Epilepsy poses significant challenges globally, with varied clinical, social, and economic impacts. Despite advances in treatment, epilepsy-related mortality remains a concern. This study aimed to analyze the demographic and regional distributions of epilepsy-related mortality in the United States (U.S.) from 1999 to 2020, identifying high-risk populations for targeted interventions. Methods: Data on death certificates were obtained from the 1999 to 2020 Centers for Disease Control and Prevention Wide-Ranging Online Study Epidemiologic Research (CDC-WONDER) database. We gathered data on demographics, place of death, and urban/rural classification. Mortality rates per 100,000 people were computed and classified according to state, year, sex, race/ethnicity, and urban/rural status. Trends were examined using Joinpoint regression. Results: A total of 12,573 deaths (age <35), 22,947 (35-64), and 21,782 (65+) were attributed to epilepsy. Mortality rates varied by age group, sex, race/ethnicity, and region. Trends showed significant increases, notably in middle-aged and older adults, with higher rates in males and nonHispani, African American populations. Conclusion: Epilepsy-related mortality exhibits demographic and regional disparities in the U.S. Understanding these patterns can guide targeted interventions to mitigate mortality risk.

Indexed as

DemographicsEpilepsyMortalityRegional distributionUnited States

Identifiers

PMID39777187
PMCPMC11704444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.