ArticleAging medicine (Milton (N.S.W))2024
Associations of arthritis with functional disability and depressive symptoms in general US adults: NHANES 1988-1994 and 1999-2018.
Article in Aging medicine (Milton (N.S.W)), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Joint Association of Functional Impairment and Depression with Advanced Cardiovascular-Kidney-Metabolic Syndrome: A Cross-Sectional and Cohort Study Using Two Large Datasets.Healthcare (Basel, Switzerland) · 2026Article
- Deriving and comparing healthy longevity distributions by gender and health prevalence measures: a statistical moments and maximum entropy approach.Population health metrics · 2026Article
- Muscle quality index correlates with arthritis: a cross-sectional study from NHANES 2011-2014.Frontiers in medicine · 2025Article
- Associations of arthritis with functional disability and depressive symptoms in general US adults: NHANES 1988-1994 and 1999-2018.Aging medicine (Milton (N.S.W)) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: This study aimed to examine the associations of arthritis with functional disability and depressive symptoms among general US adults. Additionally, it explored the relationship between radiographic knee osteoarthritis (assessed by X-ray examination) and functional disability. Above findings seek to highlight the need for comprehensive physical and mental health management in individuals with arthritis. Methods: We designed a cross-sectional study utilizing multivariable logistic regression models to examine the associations. Odds ratios (OR) and corresponding 95% confidence intervals (CI) were documented in a crude model and three adjusted models. Participants were from the National Health and Nutrition Examination Survey (NHANES) 1988-1994 and 1999-2018. Arthritis was self-reported or graded by the Kellgren-Lawrence score after an objective X-ray examination. Functional disability included disability in activities of daily living (ADL disability), instrumental activities of daily living (IADL disability), and mobility disability. Depressive symptom was assessed using the Patient Health Questionnaire (PHQ). Results: We included 22,566 older adults (≥60 years; 10,961 had self-reported arthritis) for functional disability analysis (2377 older adults with data on X-ray examination; 1012 had radiographic knee osteoarthritis) and 32,056 adults (≥20 years; 9175 had self-reported arthritis) for depressive symptom analysis. After controlling for all covariates, self-reported arthritis was associated with ADL disability (odds ratios [OR]: 2.677; 95% confidence interval [CI]: 2.499-2.868), IADL disability (OR: 2.064; 95% CI: 1.940-2.196), and mobility disability (OR: 2.954; 95% CI: 2.778-3.142), and depressive symptom (OR: 2.177; 95% CI: 1.979-2.395). In participants with data on X-ray examination, radiographic knee osteoarthritis was only associated with mobility disability (OR: 1.437; 95% CI: 1.183-1.744). Conclusions: Self-reported arthritis was associated with ADL disability, IADL disability and mobility disability, and depressive symptoms. Among participants with X-ray data, radiographic knee osteoarthritis was only associated with mobility disability in general US adults. Appropriate managements of both physical and mental health are needed for individuals with arthritis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.