Evidence map›Paper›PMID 39776895›Full record

ArticleNeuropsychiatric disease and treatment2025

The Association of Mitochondrial tRNA

Pan Jing, Haihang Yu, Wenxi Sun, Ming Liang, Tingting Xia, Haidong Yang, Peng Chen, Jin Li, Xiaobin Zhang

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pan JingDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, People's Republic of China.
Haihang YuDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, People's Republic of China.
Wenxi SunDepartment of Psychiatry, Suzhou Guangji Hospital, Suzhou, People's Republic of China.
Ming LiangDepartment of Psychiatry, Xiangshan Third People's Hospital, Ningbo, People's Republic of China.
Tingting XiaDepartment of Psychiatry, Xiangshan Third People's Hospital, Ningbo, People's Republic of China.
Haidong YangDepartment of Psychiatry, Lianyungang Fourth People's Hospital, Lianyungang, People's Republic of China.ORCID 0000-0001-8625-5474
Peng ChenDepartment of Psychiatry, Suzhou Guangji Hospital, Suzhou, People's Republic of China.ORCID 0009-0005-7563-7334
Jin LiDepartment of Psychiatry, Suzhou Guangji Hospital, Suzhou, People's Republic of China.
Xiaobin ZhangDepartment of Psychiatry, Suzhou Guangji Hospital, Suzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In this study, we examined the genetic, medical, and molecular traits of two Han Chinese families with the tRNA Methods: Clinical data and comprehensive mitochondrial genomes were collected from the two families. Variants were assessed for evolutionary conservation, allelic frequencies, and their structural and functional impacts. The study involved detailed mitochondrial whole genome analysis, as well as phylogenetic and haplotype analyses of the probands and other family members. Results: We detailed the genetic, clinical, and molecular profiles of two Han Chinese families with MDD. These families exhibited a range of depression severities and notably low penetrance of MDD. Analysis of the mitochondrial genomes revealed a homoplasmic tRNA Conclusion: The identification of the tRNA

Indexed as

Chinesehaplogroupmajor depressive disordermitochondrial DNAmutationtRNA

Identifiers

PMID39776895
PMCPMC11705967

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.