Evidence map›Paper›PMID 39776848›Full record

ArticlePatterns (New York, N.Y.)2024

Cross-modal contrastive learning for unified placenta analysis using photographs.

Yimu Pan, Manas Mehta, Jeffery A Goldstein, Joseph Ngonzi, Lisa M Bebell, Drucilla J Roberts, Chrystalle Katte Carreon, Kelly Gallagher, Rachel E Walker, Alison D Gernand and 1 more

Abstract read
In one paragraph

Article in Patterns (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. RulerNet: Learning perspective-invariant ruler representations for robust image scale estimation.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yimu PanData Sciences and Artificial Intelligence Section, College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA.
Manas MehtaData Sciences and Artificial Intelligence Section, College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA.
Jeffery A GoldsteinDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Joseph NgonziDepartment of Obstetrics and Gynecology, Mbarara University of Science and Technology, Mbarara, Uganda.
Lisa M BebellMassachusetts General Hospital Department of Medicine, Division of Infectious Diseases, Medical Practice Evaluation Center, Center for Global Health, Boston, MA, USA.
Drucilla J RobertsHarvard Medical School, Boston, MA, USA.
Chrystalle Katte CarreonHarvard Medical School, Boston, MA, USA.
Kelly GallagherCollege of Nursing, The Pennsylvania State University, University Park, PA, USA.
Rachel E WalkerDepartment of Nutritional Sciences, College of Health and Human Development, The Pennsylvania State University, University Park, PA, USA.
Alison D GernandDepartment of Nutritional Sciences, College of Health and Human Development, The Pennsylvania State University, University Park, PA, USA.
James Z WangData Sciences and Artificial Intelligence Section, College of Information Sciences and Technology, The Pennsylvania State University, University Park, PA, USA.

Funding

Microbiome-driven immune changes and growth stunting in HIV-exposed uninfected childrenR01HD112302 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI Lisa M Bebell · 2023 to 2026
$3.2M
Improving placenta imaging in women living with HIVR01EB030130 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI GERNAND, ALISON D, GOLDSTEIN, JEFFERY A · 2022 to 2025
$2.0M
HIV Infection, Placental Inflammation, and Early Childhood Outcomes in HIV-exposed, Uninfected Infants in UgandaK23AI138856 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BEBELL, LISA M · 2019 to 2023
$1.1M
NIAID NIH HHS K23 AI138856NIBIB NIH HHS R01 EB030130NICHD NIH HHS R01 HD112302
6 · The paper itself

Abstract

The placenta is vital to maternal and child health but often overlooked in pregnancy studies. Addressing the need for a more accessible and cost-effective method of placental assessment, our study introduces a computational tool designed for the analysis of placental photographs. Leveraging images and pathology reports collected from sites in the United States and Uganda over a 12-year period, we developed a cross-modal contrastive learning algorithm consisting of pre-alignment, distillation, and retrieval modules. Moreover, the proposed robustness evaluation protocol enables statistical assessment of performance improvements, provides deeper insight into the impact of different features on predictions, and offers practical guidance for its application in a variety of settings. Through extensive experimentation, our tool demonstrates an average area under the receiver operating characteristic curve score of over 82% in both internal and external validations, which underscores the potential of our tool to enhance clinical care across diverse environments.

Indexed as

contrastive learningcross-modalknowledge distillationplacenta analysisvision and language

Identifiers

PMID39776848
PMCPMC11701861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.