Atmospheric Pressure Mass Spectrometry Imaging Using Electrospray-Assisted Laser Desorption/Ionization with Gas Transportation through a Heated Tube and Minimal Sample Preparation.

Riku Hirotani, Yuto Miyoshi, Varun Sendilraj, Hisanao Hazama

Abstract read

In one paragraph

Article in Mass spectrometry (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Laser Ablation APCI-HRMS Method for the Analysis of Cultural Heritage Materials.Journal of the American Society for Mass Spectrometry · 2026
Article

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5 · Who and what money

Authors and funding

4 authors.

Riku HirotaniGraduate School of Engineering, Osaka University, A1/A14, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

Yuto MiyoshiGraduate School of Engineering, Osaka University, A1/A14, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

Varun SendilrajThe Wallace H. Coulter Department of Biomedical Engineering, 313 Ferst Dr Ste 2127, Atlanta, GA, USA.

Hisanao HazamaGraduate School of Engineering, Osaka University, A1/A14, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mass spectrometry (MS) is a valuable tool that enables label-free analysis and the ability to measure multiple molecules. The atmospheric pressure MS imaging (MSI) method usually requires tedious sample preparation. A simple ionization method with minimal sample preparation is needed for high-throughput analysis. We have developed an ion source that does not require sample preparation such as thinning, curing, planarization, or addition of matrix by the electrospray-assisted laser desorption/ionization with gas transportation (ELDI-GT). The sample is transported with nitrogen gas through a heated tube to the electrospray. The ion signal of protonated caffeine was measured under different transport conditions. The ion signal intensity was found to increase 11-fold by changing the flow rate and tube temperature from 2.8 cm

Indexed as

atmospheric pressurefocal distanceminimal sample preparation

Identifiers

PMID39776827

DOI10.5702/massspectrometry.A0167

PMCPMC11703791

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