Evidence map›Paper›PMID 39776800›Full record

ArticleTheranostics2025

Vascularized tumor on a microfluidic chip to study mechanisms promoting tumor neovascularization and vascular targeted therapies.

Magdalena Skubal, Benedict Mc Larney, Ngan Bao Phung, Juan Carlos Desmaras, Abdul Vehab Dozic, Alessia Volpe, Anuja Ogirala, Camila Longo Machado, Jakob Djibankov, Vladimir Ponomarev and 1 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Mechano-Organ-on-Chip for Cancer Research.International journal of molecular sciences · 2026
    Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Magdalena SkubalMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Benedict Mc LarneyMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ngan Bao PhungMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Juan Carlos DesmarasMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Abdul Vehab DozicMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Alessia VolpeMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Anuja OgiralaMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Camila Longo MachadoMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jakob DjibankovMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Vladimir PonomarevMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jan GrimmMolecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Exploring PSMA Biology in Tumor neovasculatureR01CA212379 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI GRIMM, JAN · 2017 to 2021
$3.5M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA212379
6 · The paper itself

Abstract

The cascade of events leading to tumor formation includes induction of a tumor supporting neovasculature, as a primary hallmark of cancer. Developing vasculature is difficult to evaluate

Indexed as

Coculture TechniquesEndothelial CellsNeovascularization, PathologicAngiogenesis InhibitorsAnimalsBevacizumabCarcinoma, Renal CellHumansKidney NeoplasmsMiceSpheroids, CellularAngiogenesis InhibitorsBevacizumabconfocal imagingmicrofluidic chipneovascularizationoptoacoustic imagingtargeted therapies

Identifiers

PMID39776800
PMCPMC11700857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.