ArticleCureus2024
Premature Calcification of Costochondral Cartilage: A Scoping Review of the Literature.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Quantification of Costal Cartilage Calcification UsingJournal of imaging · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Premature costochondral calcification is a rare finding occurring in young patients and is associated with metabolic and endocrinological conditions. Significant heterogeneity exists with regard to its definition and assessment. This scoping review aimed to summarize the prevalence, risk factors, etiology, evaluation, and management of patients with premature costochondral calcification. A scoping review was conducted in PubMed, Embase, CINAHL, CENTRAL, Scopus, and Web of Science, as well as grey literature databases, including OpenGrey and Google Scholar up to 7 December 2024 in accordance with the PRISMA for Scoping Reviews (PRISMA-ScR) checklist. Keywords related to premature calcification of costochondral cartilage were used for the literature search. A narrative review of the prevalence, risk factors, etiology, evaluation, and management of patients with premature costochondral calcification was presented. Of 152 citations, 52 articles were included in this review. Premature costochondral calcification was defined as radiological findings of costochondral cartilage calcification in a patient aged 40 years old or less. The prevalence of premature costochondral cartilage calcification ranges from 0% to 100%, with increasing incidence with age. Common conditions associated with premature costochondral cartilage calcification include hyperthyroidism, trauma/fracture, familial chondrocalcinosis, malignancy, porphyria, and Tietze syndrome. Risk factors associated with premature costochondral calcification include older age, female gender, and history of menstrual disorders. Recommended workup for premature costochondral calcification includes thyroid panel, serum calcium and phosphate, renal profile, liver profile, and vitamin D levels. Premature costochondral calcification remains a radiological finding that warrants careful medical assessment given its association with multiple pathological conditions. More research is required to understand its underlying pathophysiology, optimal initial assessment, and follow-up.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.