Evidence map›Paper›PMID 39776688›Full record

ArticleJournal of veterinary research2024

The influence of probiotic administration on selected leukocyte subpopulations and the serum amyloid A concentration in the peripheral blood of dairy cows during different lactation periods.

Piotr Brodzki, Jan Marczuk, Hubert Gorzkoś, Urszula Lisiecka, Marek Szczubiał, Adam Brodzki, Roman Dąbrowski, Leszek Krakowski, Katarzyna Głodkowska, Nikodem Brodzki

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Article in Journal of veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Piotr BrodzkiDepartment and Clinic of Animal Reproduction, Sztutowo, Poland.ORCID https://orcid.org/0000-0002-0809-2101
Jan MarczukDepartment and Clinic of Animal Internal Medicine, Sztutowo, Poland.
Hubert GorzkośGorvet Private Veterinary Practice, 09-227, Sztutowo, Poland.
Urszula LisieckaDepartment of Epizootiology and Clinic of Infectious Diseases, Sztutowo, Poland.
Marek SzczubiałDepartment and Clinic of Animal Reproduction, Sztutowo, Poland.
Adam BrodzkiDepartment and Clinic of Animal Surgery, Sztutowo, Poland.
Roman DąbrowskiDepartment and Clinic of Animal Reproduction, Sztutowo, Poland.
Leszek KrakowskiDepartment and Clinic of Animal Reproduction, Sztutowo, Poland.
Katarzyna GłodkowskaDepartment and Clinic of Animal Reproduction, Sztutowo, Poland.
Nikodem BrodzkiStudent of the Faculty of Veterinary Medicine, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-612 Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The aim of the study was to compare selected leukocyte subpopulations and the serum amyloid A (SAA) concentration in the peripheral blood of cows at different stages of lactation. The blood of cows receiving a probiotic as a dietary supplement was compared with the blood of cows not receiving it. Material and Methods: The research was conducted on 20 pregnant dairy cows randomly divided into two groups of 10 cows each. The experimental group consisted of cows given the probiotic as a feed supplement. The control group consisted of cows that were fed without supplementation. Blood was drawn six times for testing: 7 days before drying; 14 days before parturition; and 7, 21, 60 and 90 days postpartum. Leukocyte immunophenotyping was performed by flow cytometry. Results: The blood of cows administered the probiotic revealed an increased percentage of forkhead box protein 3 (Foxp3) Conclusion: The activity of the immune system in cows receiving the probiotic was higher than in control cows. However, the stabilisation of the immune system of the supplemented cows may be indicated by the persistence of a low level of SAA throughout the experiment. Therefore, it can be assumed that the immune system of cows treated with the probiotic more easily adapts to changes in conditions in particular lactation periods and that these cows become more resistant to infectious diseases.

Indexed as

dairy cowsintegrinsleukocyte subpopulationsprobioticsserum amyloid A

Identifiers

PMID39776688
PMCPMC11702246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.