ArticleJournal of veterinary research2024
Whole genome sequencing and analysis of a goose-derived
Article in Journal of veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Assessment of the pathogenicity ofJournal of veterinary research · 2026Article
- Pharmacokinetic/pharmacodynamic relationship of a novel pleuromutilin derivative APTM against Mycoplasma gallisepticum.Poultry science · 2026Article
- Pangenomic and machine learning approaches to divergent pathogenic strategies in avianFrontiers in microbiology · 2026Review
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8 authors.
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Abstract
Introduction: Material and Methods: A strain designated MG-GD01/22 was isolated from the air-sac tissues of five geese with chronic respiratory disease on a Guangdong goose farm. Its pathogenicity was assessed, antimicrobial susceptibility tests were performed using agar dilution, and its total DNA was extracted for whole-genome sequencing and gene function annotation with second- and third-generation sequencing technologies. The homology of the 16S ribosomal RNA (rRNA) region was analysed and a phylogenetic tree was constructed, as was an evolutionary tree of the Results: The isolate produced "fried egg" colonies and was pathogenic to goslings. It was resistant to enrofloxacin, danofloxacin and spectinomycin and susceptible to valnemulin, tilmicosin, tylosin, acetylisovaleryltylosin tartrate and tiamulin. The genome analysis revealed 1,666 coding genes. Gene database annotation identified 25 virulence-related genes, 22 drug resistance-related genes, 13 pathogen-host-interaction genes and 9 carbohydrate-active enzyme genes. The isolate exhibited 99.9% homology to the MG S6 strain by its 16S rRNA, while the Conclusion: This study offers theoretical references for the diagnosis, prevention and treatment of MG in geese in the Guangdong region.
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