Evidence map›Paper›PMID 39776390›Full record

ArticleJournal of assisted reproduction and genetics2025

The perception of artificial intelligence and infertility care among patients undergoing fertility treatment.

Sarah C Cromack, Ashley M Lew, Sarah E Bazzetta, Shuai Xu, Jessica R Walter

Registry-linked trialAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07308561 (The Relationship Between Quality of Life, Anxiety Levels, and Attitudes Toward Artificial Intelligence Among Women Undergoing Infertility Treatment), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07308561 recruitingnot on this map

The Relationship Between Quality of Life, Anxiety Levels, and Attitudes Toward Artificial Intelligence Among Women Undergoing Infertility Treatment

TypeobservationalSponsorAcibadem UniversityRan2025 to 2026Enrolled191ConditionsInfertility, Female, Artificial Intelligence, Quality of Life, Anxiety
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. AI in Childbirth and Emerging Alternatives to Traditional Fertility Treatments.Reproductive sciences (Thousand Oaks, Calif.) · 2026
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah C CromackDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University, 259 E Erie St Suite 2400, Chicago, IL, 60611, USA.
Ashley M LewDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University, 259 E Erie St Suite 2400, Chicago, IL, 60611, USA.
Sarah E BazzettaDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University, 259 E Erie St Suite 2400, Chicago, IL, 60611, USA.
Shuai XuQuerrey Simpson Institute for Bioelectronics, Northwestern University, Chicago, IL, USA.
Jessica R WalterDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University, 259 E Erie St Suite 2400, Chicago, IL, 60611, USA. Jessica.walter@northwestern.edu.ORCID http://orcid.org/0000-0002-8802-3391

Funding

Research Career Development in Obstetrics and GynecologyK12HD050121 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Serdar E. Bulun · 2005 to 2026
$7.2M
National Institute of Child Health and Human Development 5 K12 HD050121-18NICHD NIH HHS K12 HD050121Northwestern University Artificial Intelligence Research Grant from the Northwestern University Center for BioethicsNorthwestern University EthicsNorthwestern University Medical Humanities
6 · The paper itself

Abstract

purposeTo characterize the opinions of patients undergoing infertility treatment on the use of artificial intelligence (AI) in their care.

methodsPatients planning or undergoing in vitro fertilization (IVF) or frozen embryo transfers were invited to complete an anonymous electronic survey from April to June 2024. The survey collected demographics, technological affinity, general perception of AI, and its applications to fertility care. Patient-reported trust of AI compared to a physician for fertility care (e.g. gamete selection, gonadotropin doing, and stimulation length) were analyzed. Descriptive statistics were calculated, and subgroup analyses by age, occupation, and parity were performed. Chi-squared tests were used to compare categorical variables.

resultsA total of 200 patients completed the survey and were primarily female (n = 193/200) and of reproductive age (mean 37 years). Patients were well educated with high technological affinity. Respondents were familiar with AI (93%) and generally supported its use in medicine (55%), but fewer trusted AI-informed reproductive care (46%). More patients disagreed (37%) that AI should be used to determine gonadotropin dose or stimulation length compared to embryo selection (26.5%; p = 0.01). In the setting of disagreement between physician and AI recommendation, patients preferred the physician-based recommendation in all treatment-related decisions. However, a larger proportion favored AI recommendations for gamete (22%) and embryo (14.5%) selection, compared to gonadotropin dosing (6.5%) or stimulation length (7.0%). Most would not be willing to pay more for AI-informed fertility care.

conclusionsIn this highly educated infertile population familiar with AI, patients still prefer physician-based recommendations compared with AI.

Indexed as

Artificial IntelligenceFertilization in VitroInfertilityReproductive Techniques, AssistedAdultEmbryo TransferFemaleHumansMalePregnancySurveys and QuestionnairesArtificial intelligenceInfertilityIn vitro fertilization

Identifiers

PMID39776390
PMCPMC11950478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.