ArticleHead and neck pathology2025
Segmental Odontomaxillary Dysplasia: Unusual Tumoral Lesion.
Article in Head and neck pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Benign fibro-osseous lesions of the cranio-maxillofacial bones: an updated review with special emphasis on molecular pathogenesis.Journal of bone and mineral metabolism · 2026Review
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5 authors.
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Abstract
introductionSegmental Odontomaxillary Dysplasia (SOD) is a non-hereditary, unilateral developmental anomaly recently included in the WHO's classification of head and neck tumors. CASE PRESENTATION: Here, we report the case of an 8-year-old boy presenting with unilateral maxillary enlargement and pain without facial asymmetry. Computed tomography revealed a hypodense area in the maxillary bone with altered bone structure and osseous expansion. An incisional biopsy showed fibrous hyperplasia in the gingiva, dysplastic dentin, and reversal lines in the bone trabeculae. Following the diagnosis of SOD, the patient was referred for treatment.
conclusionTo date, only 72 cases have been reported. SOD typically manifests in early childhood, with a male predominance. While the etiology remains unclear, mutations in the PIK3CA gene have been associated with its development. Further research is needed to better understand the disease and improve patient management.
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