Evidence map›Paper›PMID 39776339›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Long‑term physical and mental Health-Related Quality of Life in Italian patients post COVID-19 hospitalisation.

Marco Viola, Carlotta Sacerdote, Giovannino Ciccone, Edoardo Donarelli, Manolis Kogevinas, Assunta Rasulo, Anna Toscano, Eva Pagano, Rosalba Rosato

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Post-COVID-19 physical and mental quality of life: a latent profile analysis and predictive factors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marco ViolaDepartment of Psychology, University of Turin (UniTO), Turin, Italy. m.viola@unito.it.ORCID http://orcid.org/0000-0003-2470-4283
Carlotta SacerdoteUnit of Cancer Epidemiology, Città della Salute e della Scienza, University-Hospital, Torino, Italy.
Giovannino CicconeUnit of Cancer Epidemiology, Città della Salute e della Scienza, University-Hospital, Torino, Italy.
Edoardo DonarelliDepartment of Psychology, University of Turin (UniTO), Turin, Italy.
Manolis KogevinasBarcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
Assunta RasuloUnit of Cancer Epidemiology, Città della Salute e della Scienza, University-Hospital, Torino, Italy.
Anna ToscanoDepartment of Psychology, University of Turin (UniTO), Turin, Italy.
Eva PaganoUnit of Cancer Epidemiology, Città della Salute e della Scienza, University-Hospital, Torino, Italy.
Rosalba RosatoDepartment of Psychology, University of Turin (UniTO), Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrior evidence suggests that patients' Health Related Quality of Life (HRQoL) worsens after COVID-19. This study aimed to investigate HRQoL in Italian patients post-hospitalization for COVID-19, focusing on changes in physical and mental HRQoL over time since COVID-19 diagnosis.

methodsA cohort of patients hospitalized for COVID-19 at Molinette Hospital in Turin, Italy, was contacted post-discharge to assess HRQoL using the SF-36 questionnaire. Patients completed the questionnaire only once at a different time since diagnosis. This design allowed for the analysis of responses up to three years after diagnosis. Measured scores were compared with normative data from the Italian population using z-scores. HRQoL differences by gender, comorbidities, and self-perception of health status before and after COVID-19 were tested. The effect of time since diagnosis on physical (PCS) and mental (MCS) SF-36 scores was analysed using multiple linear models and stratified analyses.

resultsA total of 601 patients completed the questionnaire. HRQoL was significantly lower compared to the normative Italian population. Men and individuals without comorbidities had better HRQoL, and self-perceptions of health status before and after COVID-19 influenced HRQoL. Time since diagnosis was associated with improved PCS, but MCS remained unaffected. Mental health declined in patients using anxiolytics post-COVID-19, and increasing age negatively affected physical health.

conclusionOur findings highlight the impact of time since diagnosis on HRQoL post-COVID-19 in an Italian population and suggest the need for further investigation into the pandemic's effects on HRQoL. Physicians should implement measures to improve mental HRQoL post-COVID-19.

Indexed as

COVID-19Health StatusHospitalizationMental HealthQuality of LifeAdultAgedComorbidityFemaleHumansItalyMaleMiddle AgedSARS-CoV-2Surveys and QuestionnairesLong-termPhysical and mental consequencesPost COVID-19 hospitalisationQuality of lifeSF-36Time since diagnosis

Identifiers

PMID39776339
PMCPMC11982126

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.